Samanthreddy Kedika
Visiting Research Fellow @ National Cancer Institute (NCI)
About
• 10+ yrs experience in contemporary peptide/peptidomimetic anti-cancer drug development. • Experience in the design and synthesis of bioactive peptides/peptidomimetic conjugates in preclinical drug discovery settings. • Excellent organizational skills with the ability to work independently. • Strong skills in Biorganic/medicinal chemistry, in vitro protein-based, and cell-based assays. Skills: 1. Automated and manual peptide synthesis 2. Characterization using HPLC, LC-MS, MALDI-TOF, and NMR (1H & 13C) 3. Molecular modeling: Sybyl, MOE, molsoft, 4. Assays: ELISA like assays, Fluorescence Polarization, Kinase activity assays, and Cell viability
United States
Frederick
Higher Education
Peptidomimetics, automated synthesis, Molecular Modeling, Chemical Biology, Automated synthesis, Microsoft Office, Microsoft Excel, High-Performance Liquid Chromatography (HPLC), Medicinal Chemistry, Peptide Synthesis, Drug Discovery, Liquid Chromatography-Mass Spectrometry (LC-MS), Drug Design, Nuclear Magnetic Resonance (NMR), Chromatography, ChemDraw
Experience

Visiting Research Fellow
Frederick, Maryland, United States
Working under the guidance of Dr. Terrence Burke where our primary focus is to - Decipher the role of histone post-translation modifications in HIV integration by synthesizing designer histones (Total synthesis/Semi-synthesis of proteins) - Understand the BRAF chemical biology using peptide probes (assay development and molecular modeling assisted peptide design)

Graduate Research Associate
Houston, Texas, United States
Worked under the guidance of Dr Gomika Udugamasooriya. Highlights of my research - • Developed resin synthetic methodology for the synthesis of bivalent ligands • Identified a peptidomimetic pharmacophore for a disease-relevant kinase • Optimized the ligand development for cell surface biomarker
Samanthreddy Kedika's Contact Information
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