Samanthreddy Kedika

Samanthreddy Kedika

Visiting Research Fellow @ National Cancer Institute (NCI)

About

• 10+ yrs experience in contemporary peptide/peptidomimetic anti-cancer drug development. • Experience in the design and synthesis of bioactive peptides/peptidomimetic conjugates in preclinical drug discovery settings. • Excellent organizational skills with the ability to work independently. • Strong skills in Biorganic/medicinal chemistry, in vitro protein-based, and cell-based assays. Skills: 1. Automated and manual peptide synthesis 2. Characterization using HPLC, LC-MS, MALDI-TOF, and NMR (1H & 13C) 3. Molecular modeling: Sybyl, MOE, molsoft, 4. Assays: ELISA like assays, Fluorescence Polarization, Kinase activity assays, and Cell viability

Country

United States

City

Frederick

Industry

Higher Education

Skill

Peptidomimetics, automated synthesis, Molecular Modeling, Chemical Biology, Automated synthesis, Microsoft Office, Microsoft Excel, High-Performance Liquid Chromatography (HPLC), Medicinal Chemistry, Peptide Synthesis, Drug Discovery, Liquid Chromatography-Mass Spectrometry (LC-MS), Drug Design, Nuclear Magnetic Resonance (NMR), Chromatography, ChemDraw

Experience

National Cancer Institute (NCI)

Visiting Research Fellow

National Cancer Institute (NCI)

LinkedIn
2020-7 - Present · 6 yrs 3 mos

Frederick, Maryland, United States

Working under the guidance of Dr. Terrence Burke where our primary focus is to - Decipher the role of histone post-translation modifications in HIV integration by synthesizing designer histones (Total synthesis/Semi-synthesis of proteins) - Understand the BRAF chemical biology using peptide probes (assay development and molecular modeling assisted peptide design)

University of Houston

Graduate Research Associate

University of Houston

LinkedIn
2015-8 - 2020-5 · 4 yrs 10 mos

Houston, Texas, United States

Worked under the guidance of Dr Gomika Udugamasooriya. Highlights of my research - • Developed resin synthetic methodology for the synthesis of bivalent ligands • Identified a peptidomimetic pharmacophore for a disease-relevant kinase • Optimized the ligand development for cell surface biomarker

University of Houston

Graduate Teaching Assistant

University of Houston

LinkedIn
2018-1 - 2019-12 · 2 yrs

Houston, Texas, United States

• Assistant instructor for the general principle of drug action (phar 2362) • Teaching assistant for Functional group analysis and medicinal chemistry I

Indian Institute of Chemical Biology

Volunteer Research Assistant

Indian Institute of Chemical Biology

LinkedIn
2013-6 - 2014-7 · 1 yr 2 mos

Kolkata, West Bengal, India

Indian Institute of Chemical Biology

Project Trainee

Indian Institute of Chemical Biology

LinkedIn
2012-8 - 2013-5 · 10 mos

Kolkata, West Bengal, India

Design and synthesis of Sugar-based Urea Triazole linked peptidomimetic macrocycle

Education

University of Houston

University of Houston

LinkedIn

Medicinal and Pharmaceutical Chemistry

2015-8 - 2020-5 · 4 yrs 10 mos
Kakatiya University

Kakatiya University

LinkedIn

Pharmacy

2007 - 2011 · 4 yrs

Samanthreddy Kedika's Contact Information

Email

******@***.com

Phone

(**) *** ****

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