Peyton Conley
Principal Scientist @ Eli Lilly and Company
About
Curious and passionate Senior Scientist with 7+ years of research experience in hematology, immunology, and gene therapy. Energized by advancing access to medicine and developing innovative therapies that transform lives globally. Currently driving cutting-edge programs in hematopoietic stem cell (HSC)-targeted editing and in vivo delivery for sickle cell disease—leading projects from strategy and design through execution and delivering decision-enabling data packages.
United States
Greater Boston
Biotechnology
Vector Design, Lentivirus, AAV, Fluorescence Microscopy, Karyotyping, Southern Blot, Molecular Cloning, Vector Cloning, Riboseq, In Vivo, GraphPad Prism, Microsoft PowerPoint, Scientific Communications, Cell Culture, RNAi, Global Health, Next-Generation Sequencing (NGS), Droplet Digital PCR (ddPCR), Assay Development, Laboratory Skills
Experience
Principal Scientist
Eli Lilly and Company
Genetic Medicine
Senior Scientist I
Novartis
Driving innovation in gene therapy for Sickle Cell Disease (SCD) through comprehensive study management and assay development. Skilled in validating and characterizing therapeutic gene-editing platforms using advanced molecular, cellular and biochemical techniques. Passionate about advancing global health initiatives and expanding access to transformative SCD therapies worldwide.
Research Scientist II
Novartis
Cambridge, Massachusetts, United States
Graduate Student
Dana-Farber Cancer Institute
Conducted advanced research on the role of RPS15 mutations in Chronic Lymphocytic Leukemia (CLL). Developed and validated lentiviral-transfected HG3 overexpression cell lines using molecular assays including qRT-PCR, Western blot, and Ribo-seq. Investigated B-cell dysregulation in transgenic mouse models through multicolor flow cytometry, transcriptomic, and proteomic analysis. Independently managed complex projects, coordinated experiments, and oversaw breeding and cohorts of 250+ mice.
Research Assistant
Boston Children's Hospital
Greater Boston Area
Developed innovative mouse models to evaluate immunogens for eliciting broadly neutralizing antibodies against HIV-1 and Influenza. Designed and cloned constructs for recombinant protein and antibody expression, followed by purification using FPLC for genetic modification of embryonic stem (ES) cells. Conducted ES cell screening via Southern blotting and karyotyping through fluorescent microscopy. Advanced therapeutic development by creating and characterizing anti-human PD-1 antibodies, validating candidates through protein purification and affinity analysis using ELISA.
Education
Harvard Medical School
Immunology
Boston University
Public Health- Health Equity
University of New Hampshire
Biomedical Sciences, General
Peyton Conley's Contact Information
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