Nathan Shapiro
Vice President, Head of Medicinal Chemistry @ Pallando Therapeutics
United States
San Francisco Bay Area
Biotechnology
High Throughput Screening, Target Selection, Strategic Planning, Drug Design, Pharmacokinetics, Team Leadership, Patent Applications, Synthetic Chemistry, Drug Discovery, Pharmacology, ADME, English, Molecular Modeling, Organic Synthesis, Cross-functional Team Leadership, Synthetic Organic Chemistry, Medicinal Chemistry, Project Leadership, Interpreting Data, Molecular Design
Experience
Vice President, Head of Medicinal Chemistry
Pallando Therapeutics
San Francisco Bay Area
Executive Director, Head of Medicinal Chemistry
Pallando Therapeutics
San Francisco Bay Area
Senior Director, Head of Medicinal Chemistry
Vir Biotechnology, Inc.
San Francisco, California, United States
Director, Medicinal Chemistry
Vir Biotechnology, Inc.
San Francisco, California, United States
Senior Research Scientist II
Gilead Sciences
Foster City, CA
Senior Research Scientist
Gilead Sciences
Research Scientist
Gilead Sciences
NIH Postdoctoral Research Fellow with Prof. George Whitesides
Harvard University
Cambridge, MA
• Developed two methods for monitoring protein-ligand binding using magnetic levitation. • Used calorimetry to measure energetics of protein-small molecule binding events. • Examined the effect of solvent in the formation of multiphase polymer systems. • Studied charge transfer through self-assembled monolayers.
Graduate Research with Professor F. Dean Toste
University of California, Berkeley
Berkeley, CA
• Developed several novel gold-catalyzed rearrangement and annulation reactions. • Led mechanistic investigations. • Obtained the first X-ray structure of a cationic phosphine-gold(I)-alkyne complex. • Used DFT calculations to rationalize reactivity differences between the coinage metals. • Spearheaded the development of a bonding model for gold(I) carbene complexes. • Discovered a novel enantioselective organocatalytic hydroamination reaction.
Education
University of California, Berkeley
Chemistry
Thesis title: Development and Mechanistic Investigations of Gold-Catalyzed Reactions
Massachusetts Institute of Technology
Chemistry
Nathan Shapiro's Contact Information
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