Kristina D. Chadwick, PhD, DABT
Vice President, Development Lead & Head of Toxicology @ Beeline Medicines
About
Strategic-thinking, action-oriented, problem-solving scientific leader with 25 years of nonclinical safety assessment, regulatory, and drug development experience in a highly matrixed biopharmaceutical setting spanning early development through life-cycle management. • Currently a Global Program Lead (GPL) with cross-functional leadership and overall responsibility for defining development program strategy, execution, and ensuring data-driven Go/No-Go decisions. • Previous leadership in Global Regulatory Affairs supporting early development (including IND submission) through Ph 2 as Global and/or US Regulatory Lead• Previous leadership as Drug Safety Evaluation Therapeutic Head (nonclinical toxicology) for Metabolic Diseases and Fibrosis, including scientific collaboration with Discovery and Business Development • Global Health Authority interactions• Author and/or reviewer of reports and regulatory documents (briefing packages, IND, IB, CTA, NDA/MAA) in support of the registration of multiple drug candidates and queries.• Matrix management of cross-functional teams and previous direct-line management of 4 Ph.D. scientists.
United States
Greater Boston
Pharmaceuticals
Drug Discovery, In Vivo, Science, Pharmaceuticals, R&D, Toxicology, GLP, FDA, NDA, Drug Development, Pharmacokinetics, CRO, IND, Pharmaceutical Industry, Pharmacology, Biomarkers, Immunology, Oncology, Biopharmaceuticals, Drug Metabolism
Experience
Vice President, Development Lead & Head of Toxicology
Beeline Medicines
Boston, MA
• Lead cross-functional programs for molecules targeting autoimmune diseases, ensuring strategic alignment and effective execution. • Oversee toxicology assessments to support the progression of compounds into clinical development. • Collaborate with diverse teams to drive innovation and streamline processes in drug development at Beeline Medicines.
Board Member
Duke University Graduate School
Durham, North Carolina, United States
Duke University Graduate School Board of Visitors - 3 year term
Global Program Lead, Early Development (Executive Director)
Bristol Myers Squibb
Early Development Program Lead (Sr. Director)
Bristol Myers Squibb
Princeton, New Jersey, United States
Leveraging my accumulated drug development experience, I moved to the EDPL role where I lead cross-functional compound development teams in Immunology and Cardiovascular with a focus on strategy and execution to enable successful early-stage development (through Ph 2).
Director - Global Regulatory Strategist
Bristol Myers Squibb
Princeton Pike, NJ
Following a 2019 rotation in Global Regulatory Strategy (GRS) during which I continued my DSE role, I transitioned full time to GRS to further broaden drug development acumen.
Director/Therapeutic Area Head
Bristol Myers Squibb
New Brunswick, NJ
Director in Toxicology and Therapeutic Area Head in Metabolic Diseases and Fibrosis for Drug Safety Evaluation (DSE).
Associate Director/Therapeutic Area Head
Bristol Myers Squibb
Greater New York City Area
Associate Director in Toxicology and Therapeutic Area Head in Metabolic Diseases and Fibrosis for Drug Safety Evaluation.
Principal Scientist
Bristol Myers Squibb
New Brunswick, New Jersey
Senior Research Investigator II
Bristol Myers Squibb
New Brunswick, New Jersey
Senior Research Investigator I
Bristol Myers Squibb
New Brunswick, New Jersey
Research Scientist
Roche
Palo Alto, California
Staff Scientist
Targeted Genetics
Seattle, Washington
Education
Duke University
Pharmacology/Toxicology
Dissertation focused on the developmental neurotoxicity of an organophosphate pesticide
Mount Saint Mary's University
Biochemistry
Kristina D. Chadwick, PhD, DABT's Contact Information
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