Jiaqian Li

Jiaqian Li

Senior Scientist @ Foresite Labs

About

I am a peptide and protein bioconjugation specialist with a Ph.D. in Chemistry from the University of Minnesota and industry experience at a biotech startup in Cambridge, MA. My expertise spans synthetic chemistry, lipid-based conjugation, and analytical characterization techniques, including LC-MS, HPLC, DLS, SEC, and HIC. I have designed and optimized multiple lipid-peptide and lipid-protein conjugates for therapeutic delivery, with a strong focus on biophysical and biochemical properties such as plasma stability, forced degradation, and particle size. I also actively contribute to in vitro assays such as protein degradation, permeability testing, flow cytometry, SDS-PAGE fluorescence analysis, and ELISA. My goal is to transition to a Principal Scientist role within the next 3–5 years, ideally leading a team in R&D and continuing to drive innovation in drug delivery and bioconjugation. I’m actively developing leadership and communication skills to support this growth, and I am passionate about translating complex molecular designs into viable therapeutic solutions.

Country

United States

City

Cambridge

Industry

Biotechnology

Skill

Bioconjugation, Drug Delivery, Peptide Chemistry, Protein-Lipid Conjugation, Lipid-Peptide Conjugation, Drug Delivery Systems, Organic Synthesis, Liquid Chromatography-Mass Spectrometry (LC-MS), High-Performance Liquid Chromatography (HPLC), NMR Spectroscopy, Dynamic Light Scattering (DLS), Size-Exclusion Chromatography (SEC), Hydrophobic Interaction Chromatography (HIC), Flow Cytometry, ELISA, SDS-PAGE, Protein Degradation Assay, Cell Based Assays, Permeability Testing, Cross-functional Collaborations

Experience

Foresite Labs

Senior Scientist

Foresite Labs

LinkedIn
2026-5 - Present · 5 mos

Cambridge, Massachusetts, United States

Transcera

Scientist II

Transcera

LinkedIn
2025-4 - 2026-5 · 1 yr 2 mos

Boston, Massachusetts, United States

Led design and synthesis of lipid-peptide and lipid-protein conjugates for intracellular delivery applications. Developed and executed robust workflows for conjugate characterization using LC-MS, HPLC, DLS, SEC, and HIC. Conducted comprehensive stability evaluations including plasma stability and forced degradation assays. Designed and implemented in vitro assays, including protein degradation, permeability, ELISA, SDS-PAGE with fluorescence, and flow cytometry. Collaborated cross-functionally with biology and analytical teams to integrate chemical and biological data for therapeutic assessment. Contributed scientific insights in internal project meetings and planning sessions. Currently working to mentor junior staff and improve communication of scientific results through structured presentation training.

Transcera

Scientist I

Transcera

LinkedIn
2023-10 - 2025-4 · 1 yr 7 mos

Cambridge, Massachusetts, United States

Education

University of Minnesota

University of Minnesota

LinkedIn

Chemical Biology

2017-8 - 2023-8 · 6 yrs 1 mo
The University of Hong Kong

The University of Hong Kong

LinkedIn

Chemical Biology

2015-1 - 2016-8 · 1 yr 8 mos
East China University of Science and Technology

East China University of Science and Technology

LinkedIn

Materials Chemistry

2013-8 - 2017-6 · 3 yrs 11 mos

Jiaqian Li's Contact Information

Email

******@***.com

Phone

(**) *** ****

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