Christophe Mihalcea
Director of Process Development and Technology Transfer @ Windfall Bio
About
I am an independent consultant helping start‑ups and established companies develop challenging solutions for the sustainable production of fertilizers, bioplastics, fuels, chemicals, and foods at lab‑scale, pilot‑scale, and full‑scale operations. I specialize in all aspects of Carbon Capture and Transformation (CCT) technologies that enable the circular bioeconomy through gas fermentation.I am a technical leader with a strong background in chemistry, physics, engineering, and biology, and have excelled as an individual contributor, project manager, and team leader across the gas fermentation and data storage industries. My technical depth across these disciplines has enabled me to develop innovative solutions in multiple groundbreaking technology areas. As a team leader, I have consistently focused on IP generation and sustainability while executing on long‑term technology roadmaps.I began my career as a chemist and expanded my expertise into nanotechnology—including micromachining of sensors for scanning probe microscopes—and advanced optics, such as plasmonics and nanophotonics. These skills supported my contributions to the development of a next‑generation integrated optical/magnetic recording head for high‑density data storage applications, including HAMR (Heat‑Assisted Magnetic Recording).I later transitioned into the gas fermentation space, where I have developed scalable, sustainable processes to convert waste carbon into fuels, chemicals, and proteins for nutritional use. This work has included the development of novel circular‑economy products through the mitigation of industrial CO₂ emissions. My experience spans anaerobic and aerobic continuous gas fermentation, multi‑stage fermentation processes, and the use of bacteria, yeasts, and algae. I have also integrated CO₂ electrolyzer technologies to demonstrate the feasibility of 100% substrate carbon capture and conversion into chemicals.I bring a high degree of professional curiosity and enjoy continuously learning new technologies. I am particularly drawn to early‑stage technology development through prototyping of equipment and processes, while also working to optimize existing systems for commercial deployment. With a strong interest in both process economics and environmental impact, I have been actively involved in techno‑economic analysis (TEA) and life‑cycle assessment (LCA) efforts throughout my career.
United States
Oakland
Biotechnology
Biotechnology, Fermentation Technology, Biochemistry, Chemical Engineering, Data Storage Technologies, Semiconductor Fabrication, Nanotechnology, MEMS, Thin Film Optical Waveguides, Thin Film Deposition, Electrochemistry, Wafer Bonding, Surface Chemistry, Nanoparticles and Sols, Surface Plasmon Sensors, Near-Field Optics, Nano Optics, Carbon Capture, Circular Economy, Technological Innovation
Experience

Director of Process Development and Technology Transfer
San Mateo, CA
I worked on fertilizer and living biomass production from methane using continuous gas fermentation to reduce agricultural reliance on synthetic nitrogen and mitigate methane emissions. Successfully transitioned microbes from chemical nitrogen sources to elemental nitrogen while maintaining high productivities and stable long‑duration operation, enabling a substantially reduced carbon footprint for crop production.

Director of Pilot Plant Operations
San Mateo, CA
I collaborated with external engineering teams to design a methane‑to‑fertilizer pilot plant, delivering detailed exothermic heat calculations to size cooling systems and specify required sensors and analytics. In parallel, I partnered with a contract manufacturing organization to develop an intermediate‑scale biomass production process using methanol as the carbon and energy source.

Vice President of Bioprocess Development and Innovation
Berkeley, CA
Established gas fermentation capabilities at the laboratory scale and developed a multistage continuous gas fermentation process for bioplastic production using methane as the carbon and energy source. Successfully operated the process using both concentrated methane and raw biogas sourced from a wastewater treatment facility.

Independent consultant for technology development in the fermentation and renewable energy space.

Director New Applications
Skokie, Illinois, United States
Focused on CO2 electrolyzer integration with LanzaTech’s gas fermentation technology to enable CO2 as feedstock for the production of fuels and chemicals. Demonstrated 100% carbon capture into products and biomass by successfully reprocessing bioreactor off-gases. Developed H2/CO2 multistage fermentation process in collaboration with industry partner to produce omega-3 fatty acids at very high rates and yields with acetate as intermediate product.

Director Fermentation
Skokie, Illinois, United States
Worked on single cell protein fabrication via aerobic gas fermentation. Demonstrated proof of concept of in-situ-product-stripping method that provides significant cost reduction and process facilitation for biocatalytic production of chemicals.

Team Leader Fermentation
Auckland, New Zealand
Led team of 14 scientists to develop customized laboratory set-up to enable and facilitate gas fermentation R&D. Developed efficient microbial gas fermentation process to establish a commercial ethanol and 2,3-butanediol production route. Supported development and operations of a first steel mill gas-to-ethanol pilot plant in New Zealand.

Research Staff Member
Pittsburgh, Pennsylvania, United States
Manufactured first integrated optical and magnetic recording head for Heat Assisted Magnetic Recording (HAMR) technology for extremely high-density data storage drives. Acquired extensive experience in high tech clean room environments using state of the art thin film patterning, etching and deposition systems.

Research Scientist
Tsukuba, Ibaraki, Japan
Manufactured micromachined flying head aperture array probe for high density optical data storage applications. Developed fully IC compatible single crystal silicon wet etching technique with unparalleled high etching rates and smooth surface finish.
Education
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