Anh Nhu

•Led research on rare genetic neurodevelopmental disorders, leveraging multi-omics data analysis (RNASeq, proteomics) to identify disease-modifying targets and biomarkers, driving novel therapeutic strategies. •Spearheaded preclinical drug discovery programs, facilitating progression from exploratory research to hit, lead identification, optimization. •Collaborated cross-functionally with other scientists and bioinformaticians to refine experimental design and data interpretation. •Regularly presented findings to a cross-functional team, influencing key project strategies and shaping research directions.

•Conducted in vitro and in vivo pharmacology studies, treating iPSC-derived neurons and multiple cell types, and administering P0 ICV injections in mouse models to assess therapeutic efficacy. •Developed and optimized high-throughput screening imaging and biochemical assays in 96-/384-well plates

•Investigated molecular mechanisms driving trinucleotide repeat instability in Friedreich ataxia and Huntington's disease, identifying potential genetic modifiers to inform drug development. •Developed custom PCR, qPCR, and ddPCR assays for quantitative analysis of repeat instability across mouse tissues.

•Investigated the role of heat shock protein 70 (HSP70) in breast cancer, evaluating its potential as a therapeutic target to inhibit tumor progression. •Conducted drug treatments on cancer cell lines, analyzing downstream effects on gene and protein expression, cell migration, and invasion.

•Shadow and learn basic lab techniques from a senior in her project to look at nucleolar localization signal in Dictyostelium discoideum cell

•Greet visitors at front desk • Direct family members to patients’ rooms

•Tutor children of refugees from Burma, Thailand, and Malaysia with homework after school •Help organize events for children on Saturdays