陈立凡 陈

陈立凡

Principal Investigator @ BeOne Medicines

About

AI算法工程师 | 专注大分子AIDD(AI for Drug Discovery)|百济神州 在百济神州从事AI算法的研发与落地,聚焦大分子创新药的智能化开发。主导覆盖抗体、ADC(抗体偶联药物)、工程化酶、mRNA疫苗、TCR 及 TCRm 抗体等多模态生物药的AI驱动项目。 通过构建深度学习与生成式AI模型,在靶点发现、序列设计、亲和力/稳定性预测、可开发性评估等关键环节实现算法产品化,有效推动多个早期药物管线的推进。 致力于打通AI与生物药研发的“最后一公里”,让算法真正服务于高效、精准的新药开发。

Country

China

City

Pudong

Industry

Pharmaceuticals

Skill

新药发现, Transformer模型, PyTorch, 人工智能, AIDD, 算法开发, Large Language Models (LLM), 深度学习, 药物设计, 生物信息学, 化学信息学, 人工智能药物筛选和靶标预测

Experience

BeOne Medicines

Principal Investigator

BeOne Medicines

LinkedIn
2026-3 - Present · 7 mos

浦东新区

抗体、ADC(抗体偶联药物)、工程化酶、mRNA疫苗、TCR 及 TCRm 抗体等多模态生物药的AI驱动项目。

BeOne Medicines

Senior Research Investigator

BeOne Medicines

LinkedIn
2025-3 - 2026-3 · 1 yr 1 mo

上海市, 中国

大分子AIDD,AI蛋白设计,TCR, TCRm ab,RNA Vaccine,Personalized Cancer Vaccine, Dual action antibody

BeiGene

Research Investigator

BeiGene

LinkedIn
2023-7 - 2025-3 · 1 yr 9 mos

浦东新区

从事小分子和大分子AIDD平台建设,并应用AIDD辅助新药项目。小分子平台包括:虚拟筛选,激酶谱预测。大分子平台包括:免疫原性预测,TCR设计和筛选,蛋白质从头设计,抗体性质优化等。

Education

University of Chinese Academy of Sciences

University of Chinese Academy of Sciences

LinkedIn

Drug Design

2018 - 2023 · 5 yrs
China Pharmaceutical University

China Pharmaceutical University

LinkedIn

药学(基础药学理科基地)

2014 - 2018 · 4 yrs

陈立凡 's Contact Information

Email

******@***.com

Phone

(**) *** ****

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