Zhiyong Yang

Principal scientific researcher @ Genentech

About

As a dedicated scientist, I see opportunities in challenges. With my talent and belief in technical improvement and innovation, I especially enjoy troubleshooting and problem-solving, and would like to turn more possibilities into realities.

Country

United States

City

San Francisco

Industry

Research

Skill

Liquid Handling, Problem Solving, Ex Vivo, Attention to Detail, Experimental Design, Product Management, Bioanalysis, Molecular & Cellular Biology, Embraces Change, Research and Development (R&D), Communication, Written Communication, Medical Research, Writing, Generative AI, Clinical Trials, R (Programming Language), Python (Programming Language), Cytometry, Drug Development Product Management

Experience

Principal scientific researcher

Genentech

2021-5 - Present · 5 yrs 5 mos

South San Francisco, California, United States

Senior scientific researcher

Genentech

2019-10 - 2021-4 · 1 yr 7 mos

South San Francisco, California, United States

Specialist

University of California, San Francisco

2006-4 - 2019-10 · 13 yrs 7 mos

Generated knockin reporter mice for IgE producing B cells, uncovered unique properties of these cells both in vivo and in vitro. Generated GSNOR conditional knockout mice and uncovered its essential roles in lymphocyte development

President

Association of Chinese Students and Scholars at UCSF

2013-5 - 2015-6 · 2 yrs 2 mos

Association of Chinese Students and Scholars (ACSS) at UCSF is a registered campus organization of UCSF. It represents about 700 Chinese students and scholars who work or study in UCSF. It serves as both social and professional networking platforms for its members. As its president, I oversee all aspects of operations of ACSS, including social and academic activities and external communications.

Postdoctoral associate

Baylor College of Medicine

2002-8 - 2005-11 · 3 yrs 4 mos

Established mRNA tagging method for isolating mRNA from specific tissue in Drosophila. Identified six novel photoreceptor-specific genes that may be critical in visual function. Identified genes responsible for ethanol sensitivity in Drosophila by microarray.

Postdoctoral associate

Icahn School of Medicine at Mount Sinai

2000-4 - 2002-8 · 2 yrs 5 mos

Expressed taste receptors (T1R11,2,3) in E. coli, insect cell and mammalian cells. Demonstrated that these receptors are glycosylated and can form homo- and heterodimers. Biochemical study of G-protein coupled receptor by trypsin protection, GTPgammaS binding in cell lines and primary pineal gland cell culture.

Education

Chinese Academy of Sciences

Molecular Genetics

Established a system that opened the door for the molecular study of Dunaliella salina, a green alga that is the most halotolerant eukaryote. The system consists of four parts. (1) A high-efficiency solid culture method for the wall-less alga. (2) Genetic transformation of the alga by electroporation. (3) Genomic DNA and cDNA libraries. (4) A novel gene family of carbonic anhydrase.