Zhentao Sheng
Principal Scientist @ LTZ Therapeutics
About
Experienced in Antibody Discovery and Engineering. Experienced in basic molecular mechanism of Cancer development. Have identified potential therapeutic targets for Cancer treatment. Deep knowledge of oncology and significant experience probing cellular signaling pathways (Insect hormones 20E/Juvenile hormone, Insulin/PI3K/AKT, RTK(EGFR)/RAS/MAPK, Hippo, Wnt, Notch, endocytosis, RNA binding proteins, cell cycle and cell proliferation, apoptosis, autophagy). Skilled in Real-Time Polymerase Chain Reaction (qPCR), Protein Chemistry, Molecular Biology, Cell Culture, and Immunohistochemistry, Genetics, Gene editing. Strong research professional graduated from Graduate School of Chinese Academy of Sciences.
United States
Sunnyvale
Biotechnology
Cell Biology, Molecular Cloning, Protein Purification, Molecular Biology, Cell Culture, Research, Biochemistry, Microscopy, Teaching, Fluorescence Microscopy, PCR, Confocal Microscopy, Western Blotting, Science, Protein Expression, Protein Chemistry, Immunohistochemistry, Statistics, Microsoft Office, qPCR
Experience
Principal Scientist
LTZ Therapeutics
Antibody Discovery and Engineering: phage library construction, phage display, CHO cell display; NGS; CRISPR-mediated Cell line development
Associate Principal Scientist
LTZ Therapeutics
California, United States
Antibody Discovery and Engineering, Antibody Expression in CHO cells, Antibody Purification and Characterization (HPLC, AKTA, BLI)
Senior Scientist
RubrYc Therapeutics, Inc.
Antibody Expression in CHO cells, Antibody Purification and Characterization Phage library construction, Phage display, CHO Cell display, NGS
Senior Scientist
Bright Biologics
California, United States
Antibody Discovery and Engineering: VHH phage library construction, phage display; Antibody Expression in CHO cells, Antibody Purification and Characterization
Research Professional
University of Chicago
chicago
Using fruit fly and mammalian cell line to study the molecular basis of tumor development and Growth. Identified novel EGFR/RTK signaling regulator, protein N-terminal acetyltransferases B is critical for the tumor development and growth.
Postdoctoral Researcher
University of Chicago
Drosophila Genetics and developmental cell Biology. Discovered novel EGFR signaling regulators, :Endocytosis components, N-terminal acetyltransferase B, mRNA binding protein Hrb27c, as potential therapeutic target for cancer treatment.
Postdoctoral Scholar
University of Kentucky
Lexington, Kentucky Area
Insect biochemistry and molecular biology. Molecular mechanisms through which insect hormones control development, metabolism and reproduction.
Education
Sichuan University
Biology, General
Zhentao Sheng's Contact Information
Phone
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