Zhen Shi

Senior Principal Scientist @ Genentech

About

I am a geneticist by training with extensive experience in computational biology, high-throughput genomic studies, quantitative proteomics and molecular biology.

Country

United States

City

South San Francisco

Industry

Biotechnology

Skill

Genetics, Computational Biology, Bioinformatics, Molecular Biology, Data Analysis, Python, R, Mouse Handling, Mass Spectrometry, Cell Biology, Biochemistry, Cell Culture, Microscopy, Molecular Cloning, Western Blotting

Experience

Senior Principal Scientist

Genentech

2022-7 - Present · 4 yrs 3 mos

Principal Scientist

Genentech

2017-10 - 2022-7 · 4 yrs 10 mos

United States

Postdoctoral Fellow

Stanford University

2013-9 - 2017-9 · 4 yrs 1 mo

Stanford

• Applied a quantitative proteomic approach combined with genetics and high-throughput molecular assays to study the ribosome compositions and gene regulation • Developed a bioinformatics pipeline applying Generalized Linear Model (GLM) to study the translational control of key cell signaling components, using the mammalian embryos as a model system • Performed bioinformatics analysis of mRNA translation regulation during tumorigenesis

Education

Harvard University

Genetics and Molecular Biology

2008 - 2013 · 5 yrs

Graduate student in Gary Ruvkun lab • Performed a genetic screen to identify and study new components of microRNA pathway • Applied biochemistry and mass spectrometry to study RNA modifications • Developed a bioinformatics pipeline of analyzing next-generation sequencing data, to study the evolutionary landscapes of small non-coding RNAs