Zeina El Ali - Naja , Pharm.D, Ph.D

Main Tasks : • Lead the strategic planning and execution of preclinical toxicology studies to support the development of ADC (Antibody Drug Conjugate) candidates. • Collaborate with cross-functional teams, including research and development, regulatory affairs, and clinical development, to integrate pharmacology and safety data into overall program strategies. • Design and implement in vitro and in vivo studies to assess the pharmacodynamics, pharmacokinetics, and safety profiles of ADCs. • Oversee the selection and management of Contract Research Organizations (CROs) for outsourced pharmacology and toxicology studies. • Interpret and analyze study data, prepare comprehensive reports, and present findings to internal teams and regulatory bodies. • Stay current with regulatory guidelines and industry best practices in pharmacology and toxicology to ensure compliance and scientific rigor. • Contribute to the preparation of IND applications, regulatory submissions, and scientific publications related to pharmacology and safety. • Mentor and develop team members, fostering a culture of scientific excellence and integrity. Achieved objective: IND submission and approval in 18 months (Nov-Dec 2025)

Main tasks : - Conducting in vivo Pre-clinical General Toxicology studies on different species (rodents and non rodents) - Conducting in vivo Pre-clinical DART (Developmental and Reproductive Toxicology) and juvenile studies in rodents and rabbits according to regulatory guidelines and GLP regulations - Writing Protocols - Writing General Toxicology and DART Reports - Client communication - Study coordination - Study results presentation during a Data Review Meeting with the Client

Main tasks : - Identification for raw materials, cosmetic ingredients, substances and impurities including next generation risk assessment approaches such as read-across, in silico - Risk assessment of cosmetic products based on all available data - Safety assessment of raw materials - Elaboration of ingredients (INCI) and Impurities databases - Preparation of Cosmetic Product Safety Report (CPSR) - Participating to Cosmetic Europe's meeting - Collaboration

My work consisted of: * Managing pharmacy agents * Clinical Pharmacy * Counseling * Participating in clinical and MDT rounds * Checking for drug interactions * Checking for drug preparations by pharmacy agents * Clinical Pharmacist Investigator in clinical trials * Writing protocols/reports

* Pharmacy Consultant * Supply Chain * Stock Auditor

My work consisted of : * Pharmacy hospital management * Pharmacy procurement equipment/ patient medicines/ medical & paramedical products * Preparing orders requested by each department * Organizing the pharmacy * Supply chain * Contract Negotiation * Managing Pharmacy's staff * Writing protocols

* Drugs and Diseases course * Pathophysiology course

Animal Experimentation course - Master 1 in Toxicology

My work focused on developing new in vitro techniques for detecting and evaluating the cytotoxity of new synthesized drugs on hepatocytes cells. My work included : • Scientific and practical expertise on in vitro models • Full responsibility in planning, conducting, data assessment and reporting of preclinical general toxicology studies according to regulatory guidelines and GLP regulations •Presenting data during staff meetings and conferences •Analyzing data •Writing reports