Yuewei Zhao

senior scientist @ Synoligo Biotechnologies Inc

About

** Manufacture variety of nucleic acid products; Develop edge-cutting technology/strategy for special custom projects; Test new methods/chemistry/purification tech in the field of nucleic acid chemistry and generalize the successful ones to production line. ** 12-years solid experience in organic synthesis, excellent hands-on skill on separation of complex compounds; familiar with most lab analytical methods/instruments; ** Well versed in preparation and characterization of drug metabolites-DNA/Protein addicted and the investigation on their properties and biochemical toxicological mechanism; Specialties: Organic photochemistry, Organic synthesis, photodynamic therapy (PDT); supramolecular chemistry; toxicology.

Country

City

Industry

industrial automation

Skill

nmr, hplc, organic synthesis, organic chemistry, chemistry, protein chemistry, characterization, purification, fluorescence spectroscopy, spectroscopy, biochemistry, gc ms, r&d, catalysis, synthetic organic chemistry, drug design, maldi tof, uv, science, drug discovery, dna, uv/vis, lc ms, analytical chemistry, glp, mass spectrometry, gas chromatography, fluorescence, medicinal chemistry, formulation, nanomaterials, ftir, polymer chemistry, photochemistry, column chromatography, chromatography, lifesciences, technology transfer, cell, assay development, laboratory, ir

Experience

manager of nucleic acid lab

bio-synthesis inc.

2011-10 - Present · 15 yrs

postdoctoral fellowship

nagasaki university　(長崎大学)

2004-10 - 2006-10 · 2 yrs 1 mo

* Creatively connected differenct fluorophores (fluorescein, coumarin, pyrene, etc) to cyclodextrins (Alpha, Beta, Gama) and improved the traditional TCPO chemiluminescent efficiency houndreds of times * investigated the supramolecular host-guest interactions via the cavity of cyclodextrin * utilized the cyclodextrin cavity to catalyze organic reactions * synthesized the macromolecules of the dimer or trimer of cyclodextrins, conducted under the award of JSPS (Japan Society for the Promotion of Science) fellowship.

postdoctoral fellowship

bowling green state university

2006-12 - 2008-11 · 2 yrs

* For the first time reported the systematic synthesis of pentacene derivatives via photochemical method * determined the special hand-in-hand dimer structure of tetrabromopentacene via the photoirradiated free radical connection * created a convenient method to trap the tricky, only theoretically imagined, biradicals photoformed during the photodecarbonylation to produce polyacenes

research associate

fda

2008-1 - 2011-11 · 3 yrs 11 mos

* Syntheisis, purification and characterization of (un)labelled Xenobiotic-protein or -DAN adducts * Study of Phototoxicity, hepatotoxicity of PAHs, PAs(Pyrrolizidine alkaloids) and their derivatives * Investigation of biochemical genotoxic mechanism of carcinogens.

senior scientist

bio-synthesis inc.

2011-10 - Present · 15 yrs

* Manufacture variety of nucleic acid products * Develop edge-cutting technology/strategy for special custom projects * Test new methods/chemistry/purification tech in the field of nucleic acid chemistry and generalize the successful ones to production line.