Yue-Mei Zhang
Executive Director @ Eli Lilly and Company
About
Scientific leader with extensive drug discovery experience spanning small molecule, peptide, ADC, antibody-RNA conjugate, peptide-RNA conjugate, and half-life extension technology. Track record of progressing discovery programs from screening hits into clinical candidates. Results driven program leader and highly complex problem solver by taking innovative approaches. Strategic capability and team builder. Vast experience in CRO management of integrated projects.
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United States
Pharmaceuticals
Medicinal Chemistry, Organic Chemistry, Drug Discovery, Cross Cultural Management, PEGylation, Drug Design, Project Management, CRO, Oncology, In Vivo, In Vitro, Organic Synthesis, Purification, Chemistry, Inflammation, Drug Development, Neuropharmacology, Polymers, LC-MS, Toxicology
Experience
Executive Director
Eli Lilly and Company
Boston, Massachusetts, United States
RNT Tx: Antibody/Peptide-RNA Conjugation for extra hepatic delivery; oligonucleotide modalities (siRNA, ASO, SSO, PMO)
Discovery Project Lead
Johnson & Johnson Innovative Medicine
Boston, Massachusetts, United States
SBDD small molecules for acute kidney disease (PK/PD), DNA-encoded library hit finding, macrocyclic peptides for immunology, CRO and external collaboration
Senior Director
Parabilis Medicines
Cambridge, MA, United States
Alpha-Helical Stapled Peptides, cell permeability and internalization, PROTAC
Scientific Director
Johnson & Johnson Innovative Medicine
Spring House PA
Incretin peptides, long acting antibody-peptide conjugates (phase I), dual-pharmacology drug (IND filing).
Associate Scientific Director
Johnson & Johnson Innovative Medicine
Small molecule drug discovery, peripheral restricted small molecule drugs, half-life extension technology (PEGylation, XTEN protein polymer, native proteins)
Principal Scientist
Johnson & Johnson
Spring House, PA
Small molecule drug discovery in therapeutics of metabolism, pain, inflammation, neurological disorders. Significant contributions to two NME small molecules.
Senior Scientist
Johnson & Johnson
Raritan, NJ
Scientist
Johnson & Johnson
Raritan, NJ
Senior Scientist
GSK
RTP, NC
Kinase inhibitors, SAR contribution to the discovery of EGFR/Erb-2 dual inhibitor Lapatinib.
Education
North Carolina State University
Organic Chemistry
East China University of Science and Technology
Fine Chemicals and Technology
Yue-Mei Zhang's Contact Information
Phone
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