Yogesh Chutake

Yogesh Chutake

Director, Translational Medicine @ Accent Therapeutics, Inc.

About

I am a translational medicine leader with 12+ years of expertise in oncology and neurodegenerative diseases, bridging preclinical discovery to early-phase clinical trials. Known for strategic leadership in disease biology, biomarker strategy, and assay development, I excel at driving innovative drug discovery programs targeting solid tumors, myeloid malignancies, and rare genetic diseases. As Associate Director of Translational Medicine at Kymera Therapeutics, I spearheaded the KT-253 program—a novel MDM2 degrader in Phase 1 trials—by developing biomarker strategies for proof of mechanism and biology, leading cross-functional collaborations, and managing clinical sample analysis through central labs and CRO partnerships. With a proven track record in strategic project leadership, I have successfully advanced early-stage programs to regulatory filings and clinical trials while building high-impact collaborations with key opinion leaders, academic institutions, and industry stakeholders. As a dedicated mentor, I have recruited and developed talented teams, empowering them to deliver transformative results. I thrive at the intersection of science and strategy, leveraging my expertise to unlock the full potential of translational medicine and deliver therapies that make a meaningful difference in patients' lives.

Country

United States

City

Boston

Industry

Biotechnology

Skill

Translational Medicine, Neuroscience, Biomarkers, Drug Development, Epigenetics, Molecular Biology, CRISPR-Cas9, Triplet Repeat Diseases, Next-Gen Sequencing, ChIP, Bioprocessing, Downstream Processing, Basic Biochemistry & Molecular Biology techniques, Molecular Genetics, RNA Immunoprecipitation, Cell Culture, Western Blotting, NOMe-Seq, Molecular Cloning, Polymerase Chain Reaction (PCR)

Experience

Accent Therapeutics, Inc.

Director, Translational Medicine

Accent Therapeutics, Inc.

LinkedIn
2026-1 - Present · 9 mos

Lexington, Massachusetts, United States

Independent Consultant, Translational Medicine

2025-2 - 2025-12 · 11 mos

Greater Boston

Translational development in Oncology and Neuroscience disease area.

Kymera Therapeutics

Associate Director, Translational Medicine

Kymera Therapeutics

LinkedIn
2024-1 - 2025-1 · 1 yr 1 mo

Watertown, Massachusetts, United States

Kymera Therapeutics

Principal Scientist, Translational Medicine & Biology

Kymera Therapeutics

LinkedIn
2022-1 - 2023-12 · 2 yrs
Kymera Therapeutics

Associate Principal Scientist, Oncology Biology

Kymera Therapeutics

LinkedIn
2021-1 - 2022-1 · 1 yr 1 mo

Watertown, Massachusetts, United States

Kymera Therapeutics

Senior Scientist, Oncology Biology

Kymera Therapeutics

LinkedIn
2019-8 - 2021-1 · 1 yr 6 mos
Syros Pharmaceuticals

Scientist

Syros Pharmaceuticals

2017-7 - 2019-7 · 2 yrs 1 mo

Cambridge, Massachusetts

University of Oklahoma Health Campus

Research Scientist

University of Oklahoma Health Campus

LinkedIn
2012-1 - 2017-6 · 5 yrs 6 mos

Oklahoma City, Oklahoma Area

• Extensive collaborative translational research with Biopharmaceutical industry and academic research institutes on class I HDAC inhibitors, as a therapeutic modality in neurodegenerative disease • Experience in handling primary cells, blood and tissue samples from human and humanized mouse models, and subsequent biomolecule extractions • CRISPR/Cas9 genome editing • Next-Gen sequencing, Illumina platform: Library prep to Bioinformatics analysis - high-throughput targeted bisulfite sequencing, NOMe-seq, RNA-seq • Excellent analytical, communications & interpersonal skills, with eight high impact publications • Invited talks and awards by the American Society of Human Genetics, National Ataxia Foundation, Friedreich Ataxia Research Alliance, University of Pennsylvania and Oklahoma Center for Neuroscience

University of Oklahoma Health Campus

Graduate Research Assistant

University of Oklahoma Health Campus

LinkedIn
2006-8 - 2011-12 · 5 yrs 5 mos

Oklahoma City, Oklahoma Area

- Identified a novel antisense transcript at the FXN locus - Trained undergraduate and graduate students - Trained medical students - Trained summer interns

University of Louisiana Monroe

Graduate Teaching Assistant

University of Louisiana Monroe

LinkedIn
2005-8 - 2006-7 · 1 yr

Monroe, Louisiana Area

- Taught Pharmacy Care to final year PharmD students - Trained students on professional Patient Counseling techniques - Demonstrated proper use of medication devices - Supervised and graded compounding and dispensing practices

Education

University of Oklahoma Health Campus

University of Oklahoma Health Campus

LinkedIn

Biochemistry and Molecular Biology

2006 - 2011 · 5 yrs
Savitribai Phule Pune University

Savitribai Phule Pune University

LinkedIn

Pharmaceutical Sciences

1997 - 2001 · 4 yrs

Yogesh Chutake's Contact Information

Email

******@***.com

Phone

(**) *** ****

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