Yining Xia

• Establish an expression benchmark for central dogma to validate DNA - RNA - protein dynamics in vitro and in vivo by improving the accuracy of qPCR assay and by making substantial improvements to ease & user reproducibility of nuclei acid extraction protocol and quantification • Lead molecular analysis for in vivo studies related to pharmacokinetics (PK), pharmacodynamics (PD), efficacy, and immunotoxicity • Validate the mechanism of TF dynamics and promoter activity by developing and performing protein-based assays • Evaluate accuracy of synthetic promoters in human by establishing new in vitro models of EMT that can demonstrate the prognostic capability of promoters to detect cell state