Ying Wu, Ph.D., D.Eng.

siRNA therapeutic discovery and development

Oligonucleotide chemistry, therapeutic discovery and development.

I provided expert consulting in siRNA chemistry and preclinical therapeutic development, offering strategic guidance from molecular design and optimization to in vivo validation and IND-enabling studies.

I offered advisory services in RNA and oligonucleotide therapeutic development, supporting venture capital firms and a stealth startup with target evaluation, platform differentiation, and licensing planning.

• Led siRNA project from in silico sequence hits identification to nominating development candidate with promising data in non-human primates, and all the different stages in between. • Led a project integrating machine learning (ML) with in silico siRNA design. • Integrated laboratory data and information for high throughput automation and machine learning modeling. • Oligonucleotide synthesis, bioinformatic design and CRO collaboration.

Oligonucleotide scientist