Yan Ting Z.
Chief Science Officer @ Ora Biomedical, Inc.
About
I have had a strong desire to investigate stem cells for regenerative medicine since a young age. As a post-doc research fellow, I have utilized AI-based design proteins in addition to stem cell biology to study the molecular basis of vascular regeneration using in diabetic vasculopathy organoid model. I aspire to take my skills and knowledge to companies that are also interested in developing new biotechnology for therapeutic application.
United States
Seattle
Biotechnology
Translational Research, High-throughput cell assay development, R programing, Artificial Intelligence (AI), Business Development, High Throughput Screening, Fundraising, Microsoft Solutions, Cell Based Assays, Immunofluorescence microscopy , 3D cell modeling, Research Writing, magnetic resoance imaging , Hematology, Protein Science, Protein Production, Mammalian, Binding Assays, Communication, Microsoft Office
Experience
Chief Science Officer
Ora Biomedical, Inc.
Drug development, translational research, business development, grant writing, and fundraising.
Director of Translational Science
Ora Biomedical, Inc.
United States
Research Scientist
Ora Biomedical, Inc.
Tukwila, Washington, United States
Medical Assistant - Part-time
Optispan
Human whole blood fractionation Cryopreservation of fractionated blood: RBCs, PBMCs, Plasma, and Serum Bio bank development
Postdoctoral Research Fellow at Ruohola-Baker Lab
University of Washington
Seattle, Washington, United States
NIH NIDCR T90 fellow Project 1: Identifying the functions of Tie2 receptor complexes to rescue diabetic vasculopathy Project 2: Developing novel serum-free synthetic media for optimal pluripotent stem cell culture using de novo design proteins. Project 3: Characterizing the biochemical activity of AI-designed de novo protein binders using high-throughput cell-based assays for basic science research and therapeutic application.
Graduate Research Fellow at Ruohola-Baker Lab
University of Washington
Seattle, WA
NIH NIDCR T90 fellow NIH TL1 fellow at UW ITHS Magnuson Scholar Project 1: Investigated the molecular basis of Tie2 signaling using AI-based design protein scaffolds to mitigate vascular diseases. Project 2: Utilized de novo designed high-affinity mini binder proteins to neutralize SARS-COV2 virus infection in kidney organoids and cardiomyocytes. Project 3: Performed single-cell RNA sequencing and analysis to study tooth development and devise differentiation protocols from induced pluripotent stem cells to make ameloblasts and odontoblasts. Project 4: Characterized the differentiation capacity and cellular senescence metabolism of dental pulp stem cells.
Vice President of American Dental Education Association (ADEA) - UW student chapter
University of Washington
Seattle, Washington, United States
Undergraduate Research Assistant at Kaeberlein Lab
University of Washington
Seattle, WA
Ronald E. McNair scholar Projects: 1. Yeast Replicative lifespan project - Used yeast cells with different genotypes to perform large-scale screens to understand how different genetic, environmental, and metabolic factors affect yeast aging. 2. Yeast Chronological Lifespan Project - Aimed to understand how various drugs impacted on yeasts’ lifespan over time. 3. A drugs screen project to find natural compounds that mimic the functions of rapamycin for mTor inhibition to understand the validity of the health benefits of common supplement drugs. 4. Investigation of exceptionally long-lived single mutant yeasts - Utilized R programming to search for yeast strains that lived for more than 75 divisions to identify genes and metabolic pathways that interplayed in yeast longevity.
Nuwest Research Associate
Allen Institute
Seattle, Washington, United States
Laboratory Technician
Silene Biotech (acquired by Curi Bio)
Seattle, Washington, United States
FDA-approved whole blood processing Hemopoietic stem cell biobanking
Research Intern
Swedish Neuroscience Institute - Radiology (MRI department)
Seattle WA
SNI Summer Research Intern Extension to part-time intern Project: Evaluated the correlation between MRI data and cognitive test scores of Multiple Sclerosis patients and aimed to develop a standardized model to diagnose Multiple Sclerosis at an early stage.
Lab Technician
Fred Hutchinson Cancer Research Center - Histology lab
Seattle, WA
Administrative Support
Seattle Public Utilities
Seattle
Education
University of Washington
Studied biotechnology and blood vessel regeneration
UW Magnuson Scholar
Udacity
Data Science with Python
University of Washington
Biochemistry
UW Rondal E. McNair Scholar McNair Research Funding award UW Biochemistry Research Excellence Award
Yan Ting Z.'s Contact Information
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