Xi Zhang
Senior Medical Manager @ Zai Lab
About
Clinical Research Physician with 5+ years of hands-on experience in oncology clinical development. - Expertise spans early-stage development of innovative therapeutics across diverse modalities, including monoclonal antibodies, bispecific antibodies (TCE), ADCs, and small-molecule oral agents. - Proven track record leading global trials in hematologic and solid tumors (e.g., lymphoma, SCLC, gastric cancer), securing multiple IND approvals, and achieving successful NDA submissions for novel therapies. Pioneered translational research in AI-driven functional precision medicine, developing ex vivo tumor models with machine learning-based drug response prediction systems for oncology therapeutics at Cancer Science Institute of Singapore.
China
Pudong
Pharmaceuticals
Regulotory Affairs, Clinical development strategy, Medical Monitoring, Clinical development strategy making, Regulatory Affairs, Clinical Study Design, Project Management, Data Analysis, Clinical Research, Drug Development, Molecular Biology, Microsoft Excel, MATLAB, C++, 英语, Mandarin, Data Representation, Drug Screening, Primary Cell Culture, Drug Combination Optimazation
Experience
Senior Medical Manager
Zai Lab
Shanghai, China
Medical Manager, Onco Physician, Clinical Drug Development
Zai Lab
Shanghai, China
• Zai Spirit Award, 2022 Q1
Associate Medical Manager, Onco Physician, Clinical Drug Development
Zai Lab
Pudong, Shanghai, China
• As the clinical research physician, provide medical input into early clinical development, including protocol development, medical monitoring, and clinical development strategy making. • Cooperate with external stakeholders to co-develop the license-in products, contributing to medical monitoring and regulatory submissions in late-stage clinical development. • Conduct gap analysis for Zai portfolio focusing on therapeutic area of Hematology and identify potential external opportunities in cooperation with the Business Development team.
Assistant Medical Manager, Medical Affairs
Hengrui Pharma
Shanghai, China
Technical Consultant
Biotech Connection Singapore
Singapore
♦ Biotech Connection Singapore (BCS), a non-profit organization with 2000+ members that comprises of scholars, innovators and industry professionals promoting life science entrepreneurship in biotechnology and healthcare. ♦ Carried out primary and secondary market research in a team of four consultants for a client who developed a drug discovery bioinformatics platform, focusing on markets in Singapore and Malaysia. ♦ Performed market attractiveness and competitive landscape analysis, developing business proposals and go-to-market strategies for the client.
Research Scholar, Cancer Science Institute of Singapore, YLL School of Medicine
National University of Singapore
Singapore
Explored therapeutic innovation on personalized medicine especially the novel combinational targeted therapies against rare and aggressive types of blood cancers. By using an experimental-analytical hybrid AI platform of personalized medicine, we developed a high-throughput way to optimize regimens for individual patients with different indications and accelerate preclinical drug development.
Teaching Assistant, Department of Pharmacology
National University of Singapore
Singapore
Tutored 100+ undergraduates from department of pharmacology in practical modules on Pharmacology and Pharmacokinetics.
Education
National University of Singapore
Translational Medicine on Cancer Science
By using an experimental-analytical hybrid AI platform of personalized medicine, we developed a high-throughput way to optimize regimens for individual patients with different indications and accelerate preclinical drug development. ♦ Tony B. Academic Award ♦ Research Scholarship of National University of Singapore
Nankai University
♦ First Prize Outstanding Students of Nankai University ♦ China National Scholarship ♦ Merit student of NanKai University ♦ National Encouragement Scholarship
Xi Zhang's Contact Information
Phone
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