Xinquan Liu
Senior Scientist @ Hansoh Bio
About
Pharmaceutical scientist with expertise in biologics discovery, including antibody-drug conjugates (ADCs), T-cell engagers, and siRNA-based therapeutics. Experienced in preclinical discovery and evaluation, including target selection, antibody discovery, conjugation, and functional assessment in cell-based and in vivo models.Background in tumor biology, biochemistry, PK/PD, pharmacology, and drug delivery, with hands-on experience in assay development and preclinical characterization.
United States
Rockville
Biotechnology
Pharmaceutics, Drug Delivery, Formulation, Chromatography, UV/Vis, Flow Cytometry, ELISA, Western Blotting, Fluorescence Microscopy, Nanomaterials, Chemistry, Cell Culture, Data Analysis, Microsoft Office, Lyophilization, Process Analytical Technology, Freeze drying microscopy, Karl Fischer Titration, NIR Spectroscopy, FTIR
Experience
Senior Scientist
Hansoh Bio
Scientist
Hansoh Bio
Antibody-Drug Conjugate Discovery
Postdoctoral Fellow
The University of Texas at Austin
Graduate Research And Teaching Assistant
The University of Texas at Austin
Austin, Texas Area
• Developed albumin-drug conjugates (ALDC) with controlled drug-loading for improved drug delivery in solid tumors. Evaluated the pharmacokinetics and tissue distribution of albumin-drug conjugates. • Developed albumin nanoparticles naturally targeting oncogenic KRAS cells for cancer therapy. • Contributed to synthesis, in vitro, and in vivo characterization of peptide-coated nanoparticles and antibody-peptide conjugates to overcome biological barriers. • Presented work at local seminars, national and international academic conferences. • Teaching assistant in Physical and Chemical Principles of Drugs (2016) and Pharmaceutics Laboratory (2017)
Summer Intern
Celgene
Work under guidance of Drug Product Development staff to support development of process analytical technology (PAT) tools that provide improved understanding and optimization of lyophilization process.
Research Assistant
Shandong University
• Designed and developed galactosylated TPGS-PLGA nanoparticles for drug delivery targeting hepatocyte. • Contributed to synthesis and characterization of nanoparticles including solid lipid nanoparticles, nanocrystals, and chitosan-based nanoparticles for parental drug delivery. • Fractioned polysaccharides by IEX and SEC using the AKTA purifier. Characterized physicochemical properties of polysaccharides.
Education
The University of Texas at Austin
Pharmaceutics
Shandong University
Pharmaceutics
China Pharmaceutical University
Pharmaceutic Preparation
Xinquan Liu's Contact Information
Phone
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