Vinh Nguyen, PhD

• Responsible for all phases of protocol development; communicating with supervisory staff to establish a study schedule, the sponsor to finalize the protocol and the technical staff to coordinate study initiation • Direct and/or supervise the work of technical staff in accordance with the GLP’s • Monitor the progress of studies and after consultation with senior staff, report the results to the sponsor • Participate in in-house training programs for the technical staff • Conduct literature and/or Internet searches in support of protocol or report preparation • With the assistance of senior staff, prepare posters and/or scientific paper that will contribute to the scientific reputation of Inotiv Evansville and the individual • In consultation with senior staff, prepare reports, papers and/or charts of study data for interim reports to the sponsor • Maintain knowledge of FDA and other regulatory guidelines that may affect protocol development • Inform the management of any issues affecting the conduct of preclinical studies, interaction with clients and/or generation of protocols and reports • Perform other duties as assigned • Maintain confidential information • Interact with the community and employees • Support and participate in other company initiatives as directed by management

• Investigated the role of SWI/SNF chromatin remodeling on NRF2 signaling in human cancer • Utilized a variety of techniques both wet-lab (cell culture, cloning, Western Blots) and dry-lab (Differential expression analysis, GSEA) to complete research • Self-taught R and Unix programming languages and bioinformatic techniques necessary for dissertation project • Data-mined publicly available tumor sequencing repositories (TCGA, CPTAC) to discover novel pathways that may contribute to cancer initiation and proliferation • Published first author paper demonstrating loss of SWI/SNF subunits is associated with altered KEAP1-NRF2 signaling in human cancers • Co-author publication demonstrating loss of SWI/SNF chromatin remodeling activity elevated the antioxidant NRF2 pathway, suggesting a potential mechanism for lung cancer progression and treatment resistance • Demonstrated excellent scientific presentation and writing skills, demonstrated through routine presentation of results to department and faculty across multiple disciplines • Selected for Golberg Travel Award to present scientific at Society of Toxicology, San Diego

• Advised small startup with the introduction of augmented reality video game to pediatric hospitals • Performed secondary research on the efficacy of therapeutic video games, hospital technology implementation protocols, competitive and market landscape of therapeutic video games, business models, and potential care providers to inform primary research • Conducted primary interviews with hospital administrators and care providers on their initial perception of product, target patient populations, recommendations for improving the product, and management of workflow for implementation • Honed client-facing presentations, client management, development of interview discussion guide through regular feedback from program mentors • Contributed to the development of final deliverable summarizing product feedback, how hospital decision makers will implement new technologies, and the ideal patient populations. Key recommendations included grant applications and marketing product toward Child Life Specialist and cystic fibrosis patients

• Evaluated grant proposals to the NC State Office of Information and Technology. Utilized ResultID database searching platform to determine novelty, market potential, and competitive landscape of a diverse range of technologies examples (e.g. new COVID-19 diagnostic tools, biometric monitoring fabrics for law enforcement, new insulin production technologies etc.) • Criteria for evaluation and research included: market sizing and growth projections, identification of barriers to entry, competitiveness, current development level of proposed technologies, quality of business advisors and partnerships • Reports included recommendations to NC State Office of Information and Technology on decision to fund/not fund the proposal • Identified as “top intern” by project manager, which resulted in staffing on additional projects. Produced reports at 100% over required quota

• Acted as the primary liaison of peptide synthesizer service and performed operation maintenance of machinery and training of machine operation. Synthesized peptides were used by various labs and companies. • Displayed strong laboratory practices through the upkeep of equipment, restocking of reagents, record keeping of supplies and materials, and general organization and cleanliness of lab • Performed supplementary experiments to assist lab members- Data was presented at Human Proteome Organization 2017 and published in the Journal of Proteome Research • Demonstrated strong multi-tasking skills, organization, and communication through the management of undergraduate volunteers. Trained undergraduate volunteers in lab techniques and safety protocols. Facilitated communication between undergraduates and their mentors and oversaw the