Valerie Vivat

Valerie Vivat

Principal Scientist @ Flare Therapeutics

About

- Broad curiosity in the multifaceted world of biological sciences. - PhD work in neuroendocrinology of the reproduction (Paris VI university) focused on progesterone mechanisms of action contributing to myometrium quiescence during gravidity and the changes that occur at the onset of parturition. - Post-doctoral work (at Roussel Uclaf, Paris, and at IGBMC, Strasbourg) focused on Nuclear Hormone Receptor structure/function relationships and involved transversal collaboration with structural biologists and biochemists to understand, at the molecular and structural levels, the mechanisms involved in the transduction of hormonal signal and the determinants providing hormonal selectivity. This period in the mid-90's was really overwhelming as several major labs over the world including IGBMC made substantial and fundamental discoveries in the field. - Late 90’s, I had the great opportunity to join the Oncology Department of Bristol-Myers Squibb (Lawrenceville, NJ) where I have gained knowledge in drug research, target ID and validation, and grown as a pharmaceutical-oriented scientist. - Interested and keen about biophysical and structural technologies providing significant support to the screening and characterization of small molecule interactions, I have contributed at Novalix (Strasbourg) to the development of a variety of biotechnological and biophysical techniques (native MS, ITC, DLS applied to small molecules, cell-based assays) and broadened my experience as project manager, leading research contracts with transversal contribution of various disciplines. - Effective team manager; create enthusiastic and dynamic team environment based on confidence in each one capabilities and harmony. - Knowledge and specialties: Endocrinology, Oncology, Nuclear Hormone Receptor field, Epigenetics, Biophysics, Native Mass Spectrometry, ITC, DLS, Cell Biology, Molecular Biology

Country

United States

City

Greater Boston

Industry

Pharmaceuticals

Skill

Medicinal Chemistry, Drug Design, Lead Change, Translational Medicine, Structural Biology, Biochemistry, Drug Development, Pharmacology, Biomarkers, Cell Biology, Mass Spectrometry, Biopharmaceuticals, Protein Purification, High Throughput Screening, Lifesciences, Protein Chemistry, Life Sciences, Drug Discovery, Biotechnology, Molecular Biology

Experience

Flare Therapeutics

Principal Scientist

Flare Therapeutics

LinkedIn
2021-11 - Present · 4 yrs 11 mos

Cambridge, Massachusetts, United States

Constellation Pharmaceuticals

Principal Scientist

Constellation Pharmaceuticals

2021-2 - 2021-11 · 10 mos

Cambridge, Massachusetts, United States

Constellation Pharmaceuticals

Senior Scientist

Constellation Pharmaceuticals

2016-12 - 2021-2 · 4 yrs 3 mos

Greater Boston Area

Novalix

Head of Mass Spectrometry, Molecular and Cellular Biology"

Novalix

LinkedIn
2004-7 - 2016-8 · 12 yrs 2 mos

Illkirch, Alsace, France

The mass spectrometry department in NOVALIX is dedicated to screen and characterize protein/ligand complexes using native mass spectrometry.

Bristol Myers Squibb

Research investigator

Bristol Myers Squibb

LinkedIn
1998 - 2003 · 5 yrs

Lawrenceville, NJ, USA

IGBMC

Post-Doctoral position

IGBMC

LinkedIn
1994-10 - 1998-12 · 4 yrs 3 mos

Illkirch, Alsace, France

Structure function relationships of nuclear hormone receptors

Roussel Uclaf

Post-Doctoral position

Roussel Uclaf

1992-1 - 1994-9 · 2 yrs 9 mos

Romainville, Ile de France, France

Structural determinants for steroid receptor hormonal selectivity

Education

Pierre and Marie Curie University

Pierre and Marie Curie University

LinkedIn

Reproductive physiology

1988 - 1992 · 4 yrs

Valerie Vivat's Contact Information

Email

******@***.com

Phone

(**) *** ****

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