Valeria Rodriguez

•Lead compound solubilization and inventory auditing for dry powder and solution libraries, ensuring accuracy, traceability, and compliance across internal systems. •Drive the optimization and restructuring of Compound Management (CMG) workflows to improve efficiency, scalability, and data integrity. •Lead revisions to CMG SOPs, optimizing procedures to align with evolving workflows and operational needs. •Serve as a central point of contact for compound requests, prioritizing and coordinating timelines across scientific teams. •Register and manage compounds in CDD Vault for internal research and external CRO shipments, ensuring accurate tracking and documentation. •Manage and coordinate incoming and outgoing CRO compound orders, including receipt, verification, solubilization, inventory tracking, and storage. •Prepare and deliver assay-ready plates to support scientist-driven screening, validation, and follow-up studies. •Collaborate cross-functionally with scientists and external partners to streamline compound flow from registration to experimental use.

Compound Management (CMG): •Prepared and fulfilled 800+ monthly dry powders and solutions compound requests, with high accuracy in 96, 384, and 1536-well formats, while maintaining and auditing mother/daughter plate libraries and inventories, streamlining workflows and accelerating timelines across 50+ active drug discovery programs. •Oversaw compound registration, barcoding, storage, and tracking using in-house CMG software, while utilizing automated liquid handling systems to streamline storage and retrieval. •Collaborated cross-functionally with scientists to ensure the accurate delivery of samples both onsite and off-site. Performed routine quality control checks, promptly addressing data discrepancies to enhance inventory accuracy to support ongoing research activities. High-Throughput Screening (HTS): •Performed HTS for 50+ biochemical and cell-based projects across diverse biological targets using advanced automation platforms on 384 and 1536 well formats. •Developed and executed a 100K compound β-arrestin agonist screen, performing primary screening, hit confirmation, dose-response studies, and SAR validation assays to identify promising candidates. •Conducted primary screens, hit confirmations, and dose-response studies for 13 projects while performing Western blot analyses to validate protein expression and signaling pathway activation in cell-based assays. •Recorded, analyzed, and maintained detailed documentation of screening data and experimental results of 13+ projects using PRISM and Spotfire softwares. Tissue Culture: •Conducted routine maintenance and subculturing of mammalian cell lines, ensuring the highest standards of sterility and consistency to support reliable experimental outcomes. •Prepared and sterilized culture media, buffers, and reagents, optimizing conditions for cell growth. •Performed various cell-based assays, including viability and cytotoxicity assessments.

• Assisted in event planning for educational programs housed under the CREATE initiative at UC San Diego, focused on promoting equity in education and access. • Led coordination of undergraduate-focused events and supported STEM outreach and exposure events for underrepresented communities across San Diego. • Designed program brochures, flyers, and media marketing materials using Canva, and managed outreach through Mailchimp, WordPress, and social media to promote upcoming events and maintain engagement. • Supported various administrative and logistical tasks including scheduling, communications, and collaboration with campus and community partners. • Updated and maintained databases, scanned and organized documents, filed program-related paperwork, conducted computer data entry, and assisted with collecting and tracking participant data for evaluation. • Prepared class materials and supported the day-to-day operations of educational programs. • Handled travel and reimbursement processing through CONCUR, ensuring accurate and timely submission of program-related expenses.