Tuo Chen

Industrial PHD Student @ Oniria Therapeutics

About

I graduated from the University of Barcelona with a B.S. in Chemistry and an M.Sc. in Organic Chemistry. I'm a result-oriented and highly motivated person who thrives on analyzing experimental results and achieving meaningful outcomes. My passion for research and innovation, especially in the field of medicinal chemistry, drives me to continuously learn and grow. I'm a organised person and a fast learner with a strong sense of responsibility and a knack for solving complex problems.

Country

Spain

City

Greater Barcelona Metropolitan Area

Industry

Biotechnology

Skill

Problem Solving, HPLC-MS, Chemical library, Drug screening, ChemDraw, SciFinder, Drug Discovery, Drug Design, Analytical Methods Development, R&D Management, Project Management, Report Writing, QC Tools, Stock Management, Raw Materials, Industrial Process, Technical Sales, Good Manufacturing Practice (GMP), Medicinal Chemistry, Nuclear Magnetic Resonance (NMR)

Experience

Industrial PHD Student

Oniria Therapeutics

2023-10 - Present · 3 yrs

Barcelona, Catalonia, Spain

Rational design, synthesis, chemical and biophysical characterisation of inhibitors and degraders of the epigenetic protein TET2. Under supervision of Dr. Carles Galdeano and Dr. Elsa Martínez

Chemical R&D Technician

Oniria Therapeutics

2023-6 - 2023-10 · 5 mos

Barcelona, Catalonia, Spain

• Design and synthesis of new compounds in the Hit-to-Lead and Lead Optimization process of drug discovery. • Execution of different synthesis methodologies for the improvement of candidate scale-up. • Production of the necessary quantities for subsequent biological evaluation. • Maintenance of the equipment and facilities of the research chemical laboratory to keep them operational. • Participation in scientific meetings and data interpretation.

Research Chemist

Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

2023-2 - 2023-7 · 6 mos

Barcelona, Catalonia, Spain

Master Thesis: “New approaches to the generation of high-energy intermediates in organic synthesis” under supervision of Dr. Alexandr Shafir. - Experimental research in the field of synthetic methodology. - Design and study on reactivity of C-X and C-B compounds as intermediates for radiopharmaceuticals used in PET (i.e., 18F-FDG). - Analysis with 1H, 11B, 13C, 19F RMN, 2D RMN and GC-MS, HPLC-MS. Thesis rewarded with honors (Matricula d’honor).

Research And Development Chemist

Henkel

2022-4 - 2022-10 · 7 mos

Barcelona, Catalonia, Spain

- Chemical formulation specialised in insecticide products. In accordance with Biocidal Products Regulation (BPR). - Determination of physicochemical parameters (HPLC, GC, pH, flash point, etc.). Analytical Method development. - Performance tests of formulations - General chemical laboratory maintenance - Preparation of laboratory reports and specifications sheets - Management of tests performed in external laboratories - Support for lab audits.

Student Researcher

Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

2021-9 - 2022-3 · 7 mos

Barcelona, Catalonia, Spain

Final degree project: “compounds with unusual halogen, boron and silicon groups as entry point to new reactivity patterns”. Under the supervision of Dr. Alexandr Shafir. Project rewarded with Matricula d’honor.