Tianliang Zhang
Research Associate @ UT Southwestern Medical Center
About
PhD-trained scientist with 7+ years of experience in translational oncology, tumor biology, immunology, and virology, with strong expertise in in vivo pharmacology and immune-based cancer research. Proven ability to design and execute integrated in vitro and in vivo studies to investigate tumor biology, immune responses, and therapeutic mechanisms. Hands-on experience in murine tumor models, xenografts, and preclinical efficacy studies, combined with strong capabilities in molecular and cellular biology, including CRISPR/Cas9 gene editing, molecular cloning, qPCR, Western blotting, and RNA-seq-guided target exploration. Experienced in T cell biology and viral vector systems, including T cell isolation, activation, expansion, and culture, as well as lentiviral vector packaging, titration, and transduction workflows. Skilled in multi-color flow cytometry, cytotoxicity assays, ELISA, and immune phenotyping. Strong track record of leading independent research projects, troubleshooting complex experimental systems, and translating mechanistic findings into actionable preclinical insights. Co-author of publications in journals including The Journal of Clinical Investigation and Nature Metabolism. Core areas of expertise include: Translational oncology and tumor biology In vivo pharmacology and murine tumor models CRISPR/Cas9 and functional genomics Flow cytometry, qPCR, Western blotting, and histology Mechanism-of-action studies and pathway biology Preclinical study design and cross-functional scientific collaboration I am currently exploring industry opportunities in immuno-oncology, cell therapy, in vivo pharmacology, and translational research.
United States
Dallas
Biotechnology
CRISPR/Cas9, Molecular Cloning, scRNA-seq, RNA-seq, ELISA, Flow Cytometry, Viral Transduction, Lentiviral Vector, Tumor Immunology, In Vivo, Research Skills, Research and Development (R&D), Research, Teamwork, Product Development, Volunteering, Cell Biology, Molecular Biology, Cancer Biology, Virology
Experience

Research Associate
Dallas, TX
Lead independent translational oncology projects evaluating Hippo pathway signaling and membrane-associated regulators in cell competition and tumorigenesis using liver and small-intestine models. Design and execute in vitro and in vivo studies integrating cell culture, molecular biology assays, histology, and murine models to characterize pathway regulation and tumor phenotypes. Drive project planning, troubleshooting, data interpretation, and communication of findings across multiple concurrent studies. Prepare internal scientific summaries and contribute to hypothesis generation for future target and pathway exploration.

Visiting Researcher
Rutgers Cancer Intitute of New Jersey
New Brunswick, New Jersey, United States
Tianliang Zhang's Contact Information
Phone
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