Tejas Lahoti MS, Ph.D., DABT
Principal Scientist @ Atrium Therapeutics
About
American board-certified toxicologist leader with extensive experience in leading drug discovery toxicology programs, and growing experience in development. Experience in leading diverse drug platforms and modalities with extensive understanding of mechanistic toxicology, biomarker discovery/validation using ex vivo or in vivo models. Responsible for leading and implementing nonclinical safety strategies to provide target safety assessment, develop and execute key risk mitigation studies, and identify safety differentiation strategies to enable drug discovery and development.
United States
San Diego Metropolitan Area
Pharmaceuticals
In Vivo, In Vitro, Molecular Biology, Pharmacology, Toxicology, Animal Work, Drug Development, Animal Models, GLP, Cell Culture, Pharmaceutical Industry
Experience
Principal Scientist
Atrium Therapeutics
San Diego Metropolitan Area
Transitioned to Atrium Therapeutics (SpinCo) following the Avidity–Novartis merger. Serves as Lead Project Toxicologist, providing nonclinical safety strategy and oversight to support the discovery and development of antibody–oligonucleotide conjugates (AOCs) focused on precision cardiology for genetically defined cardiomyopathies. Subject matter expertise: Nonclinical and translational safety assessment, de-risking of novel delivery platforms, strategic drug development
Principal Scientist
Avidity Biosciences, Inc.
San Diego, CA
Project toxicologist supporting discovery and development of antibody-oligonucleotide conjugates (AOCs) Subject matter expert: De-risking novel delivery platforms
Scientific Associate Director
Takeda
San Diego Metropolitan Area
Left Takeda after the San Diego site was shutdown and relocating for the opportunity to Takeda Boston was not a right fit for my family. Project Toxicologist supporting discovery and development of conjugated-oligonucleotides, small molecules, and biologics programs. Takeda subject matter expert: Oligos, molecular glues, and PROTACs
Principal Scientist
Takeda
San Diego Metropolitan Area
Project Toxicologist supporting early discovery of conjugated-oligonucleotides, small molecules, and biologics programs.
Principal Scientist
Bristol Myers Squibb
San Diego, California, United States
Nonclinical drug development - Discovery/Investigative Toxicology; Project Toxicologist on molecular glues and PROTACs
Senior Scientist
Bristol Myers Squibb
San Diego, California, United States
Investigative and mechanistic toxicology
Scientist II, Toxicology
Bristol Myers Squibb
Greater San Diego Area
Investigative and mechanistic toxicology
Scientist II, Toxicology
Celgene
Greater San Diego Area
Nonclinical drug development - Exploratory/Investigative Toxicology
Toxicologist II
Avon
Greater New York City Area
Human- and Environmental-health risk assessment, regulatory toxicology, product safety assessment, product development.
Graduate Research Assistant
Penn State University
University Park, PA 16802
1) Identifying role of Aryl Hydrocarbon Receptor (AHR) in rheumatoid arthritis . 2) Determining the regulatory role of AHR in the expression of cytokines and chemokines. 3) Role of humanized AHR (Ttr)/Cre(Alb)/LoxP/(fx/fx) mice in TCDD-mediated toxicity and its comparison with the Cre(Alb)/LoxP/(fx/fx) and AHR (b/b) allele.
Toxicology Intern
ExxonMobil
Greater New York City Area
Teaching Assistant
Long Island University
Greater New York City Area
1) Assisted in Experimental methods in Pharmacology and Toxicology lab (PTM 802 graduate level lab course) during Spring-2007, -08 and -09 semesters. 2) Assisted in Advance Microbiology lab (PH 131) for 4th year PharmD students during the Fall-2007, -08 and Summer-09 semesters.
Graduate Research Assistant
Long Island University
Greater New York City Area
Worked on: 1) Examining the bicarbonate-chloroprocaine interactions with or without epinephrine in a sciatic nerve block. A collaborative research supported by New York Methodist Hospital 2) Long Term Exposure Effects of Nutraceuticals on Cerebral Apoplexy, and Cardioprotective Activity in rats. Sponsored by Cho-Seon Pharmaceuticals.
Education
Penn State University
Molecular Toxicology
Long Island University
Pharmacology and Toxciology
Savitribai Phule Pune University
Pharmacy
Tejas Lahoti MS, Ph.D., DABT's Contact Information
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