sudhir raghavan

My postdoctoral work at the SCC involved synthesis of probe molecules against targets such as the two-pore potassium channel (KCNK9), Venezuelan Equine Encephalitis viruses (VEEV) and Nuclear factor (erythroid-derived 2)-like 2 (Nrf2). The synthesis of small heterocyclic molecules for these projects involved enantioselective synthesis, chiral HPLC resolution of diastereomers, click chemistry and other contemporary organic chemistry techniques. Additionally, I have working knowledge of parallel synthesis using miniblocks and flow chemistry using Vapourtec.

Synthesis of heterocyclic molecules and computational methods in the design and optimization of small molecules interacting at several biological targets. I am a self-taught user of in silico drug design techniques and have routinely used Sybyl, Gold, Flexx (LeadIT) and MOE in my doctoral research. My research involved development and validation of homology models, docking studies to interpret observed SAR and development of 3D-QSAR models including COMFA and topomer COMFA models. Drug targets include receptor tyrosine kinases, dihydrofolate reductase, thymidylate synthase, tubulin, GAR FTase and AICAR FTase.

MD Anderson has built a worldwide reputation for excellence in cancer patient care, research, education and prevention. We couldn't have done it without our top-notch faculty and staff, or the generous spirit of volunteers and community members who donate everything from free time to pints of blood to help us in our mission to end cancer. Our various departments work as a team to deliver multidisciplinary cancer care, a concept pioneered by MD Anderson.You can view all of our career opportunities at careers.mdanderson.org.

Summer project with Roche, India: Customer (nephrologists, patients) satisfaction survey for post-transplant patients and estimation of out-of-pocket costs of patients over the treatment period in non-treatment costs.in Mumbai, India.