Sebastien Sannajust

Contributed to the development and execution of Nonclinical Safety Programs from Discovery through late stage Clinical Development Programs Assist in the writing of regulatory documentation (IND, CTA) Manage CRO interactions for Discovery and Nonclinical studies Spearhead protocol, data, and report reviews Lead cross-functional meetings with CMC, Research, Bioanalytical, and Nonclinical representatives

Led scientific collaboration with Glaxo-Smith-Kline producing data aligned with their novel compound - GSK3858279 in Phase I using in-vitro screening methods (neuronal culture, calcium imaging) and in-vivo assays (surgery-induced modeling, nociceptive and movement behavior, necropsy, histopathology, and imaging). Managed animal and reagent procurement for laboratory Worked with PI to develop budget strategies for laboratory procurement and grants. Represented team in regulatory affairs - DEA, IACUC, AAALAC, EH&S, OSHA Implemented FDA-approved auditing tools for laboratory Partnered with colleagues to investigate effects of pain on the microbiota using in-vivo and in-vitro assays

Spearheaded numerous projects (4+) using in-vivo modeling of osteoarthritic and bone cancer pain Managed and taught undergraduates and medical students survival surgery techniques, cell culture, and animal behavior (13 direct reports)