Sibo Jiang

Associate Director of Oligonucleotide Process Development in a fast-paced CMO cGMP environment responsible for development and on-time delivery of processes for medium to large scale manufacturing of complex oligonucleotide APIs to support from pre-clinical to phase I/II/III programs. Specialized in solid-phase synthesis, cleavage/deprotection, purification and downstream processing of complex oligonucleotide APIs. Proficient in project planning, scale-up/down modeling, technology transfer, proof of concept manufacturing, process characterization/optimization/validation, DoE design/experimentation/analysis, root cause investigation, drafting/reviewing GMP documents.

-Supervise a group of process development chemists and scientists providing project estimation and technical managements for multiple multi-million projects -Work closely with other departments and external teams that include clients and consultants to ensure on time in full delivery of projects -Manage the planning and execution of a process validation program that include process characterization using DoE approach, demonstration runs, PPQ batches and etc. -Lead cross-site process alignment activity updating Avecia's Oligo technology platform

Responsible for project/raw material planning, scale up/down modeling, proof of concept manufacturing, process optimization, non-GMP production and process transfer to large scale cGMP manufacturing of novel oligonucleotide APIs in support of from pre-clinical development to toxicology studies as well as phase I/II clinical studies.