Shuangyi Wan
Principal Scientist - Senior Director @ WuXi AppTec
About
Ph.D. in Organic Chemistry • Have completed the total syntheses of THREE biologically active natural products • Have developed THREE useful methodologies and two of them have been successfully applied to the total syntheses of three complex natural products • Two year industrial experience as a medicinal chemist • Hands-on experience in design/synthesis of complex molecules • Extensive experience in structure-activity relationship (SAR) studies • Excellent communication skills and strong ability to identify and solve problems Specialties: • Extensive hands-on experience in multi-step organic/chiral synthesis of complex molecules • Analytical methods: 1D & 2D NMR, FT-IR, LC-MS, HPLC (achiral and chiral), UV-Vis, TGA • Separation methods: flash chromatography, prep-TLC, MPLC, reverse phase/chiral prep-HPLC • Proficient with Scifinder, Beilstein, ISI Web of Knowledge, ChemOffice, MS Office • Other skills: microwave synthesis, solvothermal synthesis, high pressure reactions, lyophilization
China
Pudong
Pharmaceuticals
LC-MS, Mass Spectrometry, Organic Chemistry, HPLC, NMR, UV/Vis, FTIR, Organic Synthesis, Drug Discovery, SciFinder, ChemDraw
Experience
Principal Scientist - Senior Director
WuXi AppTec
Shanghai
Research Investigator
Pamlico Pharmaceutical Inc
Research Triangle Park, NC
Postdoctoral Associate
University of Pittsburgh
Greater Pittsburgh Area
Total synthesis and structure-activity relationship studies of antitumor natural product (+)-psymberin and analogues
Senior Research Scientist
Albany Molecular Research, Inc
Albany, New York Area
Design and synthesis of small molecules with antidiabetic and anticancer activities to support the drug discovery projects
Graduate Researcher
University of Pittsburgh
Greater Pittsburgh Area
1. Total synthesis of antitumor natural product (+)-dactylolide 2. Total synthesis of protein phosphatase inhibitor natural product (+)-lactodehydrothyrsiferol 3. Polycyclic ether synthesis through epoxide opening cascades 4. Multicomponent synthesis of oxidized amides through nitrile hydrozirconation 5. Polymer-supported aldehyde and ketone synthesis through cyclo-release
Education
University of Pittsburgh
Organic Chemistry
Nanjing University
Chemistry
Shuangyi Wan's Contact Information
Phone
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