sarah hanson

associate director, assay development

About

Experienced project leader, team leader, line manager, and mentor in technical innovation. Strategic thinker with the ability to inspire scientific excellence and cross-functional collaboration to bring material solutions to long-standing challenges and to drive technology advancements from concept to commercialization. Strong track-record of developing biological technology for industrial applications, with current emphasis in the development of new medical diagnostics for cancer. Enthusiastic and organized with excellent communication, writing, and presentation skills. Specialties: assay development, biomarkers, diagnostics, industrial enzymes, alternative energy, glycobiology, glycoproteins, enzymology, biochemistry, glycomodifying enzymes, chemo-enzymatic synthesis, sulfatases, inhibitors, glycoproteomic probes, Design of Experiments, statistics, statistical process control

Country

united states

City

san diego

Industry

biotechnology

Skill

biochemistry, protein chemistry, chemistry, assay development, protein expression, molecular biology, enzymes, science, protein purification, characterization, high throughput screening, biofuels, cell culture, pcr, proteomics, hplc, purification, laboratory, glycobiology, mass spectrometry, drug discovery, biophysics, chromatography, organic chemistry, product development, lc ms, protein engineering, team management, program management, medical diagnostics, strategic planning, cap/clia, structural biology, immunoassays, biomarkers, oncology, verification and validation, immunofluorescence, cancer research, risk assessment, design contol, clinical development, resource management, quality assurance, translational research, clinical research, bioanlytical, biotechnology, life sciences, cell biology

Experience

senior research associate

basf

1999-1 - 2002-1 · 3 yrs 1 mo

Diversa now BASF Enzymology Department: Discovery, evolution, and high-throughput screening of enzymes for industrial processes. Responsible for protein expression, biochemical evaluation, and assay development.

director, assay development

truvian sciences

2017-12 - 2018-12 · 1 yr 1 mo

manager, biopharma assay development

epic sciences

2015-10 - 2016-1 · 4 mos

* Manager of assay development on the Epic platform. Developed and maintained external partnerships with academic research institutions and pharmaceutical companies. Authored statements of work * devised strategy * supervised assay development activities * delivered technical reports and presentations * transferred assays into the clinical lab for patient testing in compliance with quality and regulatory.

staff scientist

the scripps research institute

2007-9 - 2011-6 · 3 yrs 10 mos

* Advisor: Chi-Huey Wong * Collaborators: Jeff Kelly, Jane Dyson, Ben Cravatt, Martin Lotz, Ian Wilson * Developing engineering principles for stabilizing and enhancing the yields of proteins via N-glycosylation. * Developing inhibitors and mechanism-based probes against glycomodifying enzymes involved in disease; bioanalytical characterization methods including LC-MS/MS * Lab oversight and grant/manuscript preparation. * Graduate Course Instructor for “Bio-organic Chemistry 2010,” covering three lectures on glycobiology

graduate research

the scripps research institute

2002-9 - 2007-9 · 5 yrs 1 mo

Advisor: Chi-Huey Wong Investigations into glycan function through the production of homogeneous glycoproteins and the development of glycomic methods to monitor enzymatic transformations.

honors undergraduate research

uc berkeley

1998-1 - 1999-1 · 1 yr 1 mo

Advisor: Peter G. Schultz Synthesis and characterization of 2,6,9-trisubstituted purine library and screening for structure activity relationships in microtubule assembly assay. Biochemical evaluation of purine inhibitors against cdc28 from S. cerevisae.

fellow, research experience for undergraduates

national science foundation

1998-6 - 1998-8 · 3 mos

Advisor: Maria C. Linder Evaluation of the biological time-course distribution of high-specific activity 110Ag(I) to serum proteins and organs in rats.

director, assay development

epic sciences

2016-1 - 2017-9 · 1 yr 9 mos

Cross-functional group leader in the development of assays to detect clinically actionable cell status in peripheral blood samples using the Epic Platform technology, a combination of immunocytochemical fluorescent staining, cell imaging, and computer-assisted cell detection; follow-on next-generation sequencing of circulating tumor cells. Product Development including Verification and Validation (V&V) and technical transfer activities to deliver laboratory developed tests (LDTs) into the clinical lab. Experience with oncology diagnostics, assay development, immuno-assays, ELISA, bioanalytical assays, microscopy, imaging, clinical research, transitional research, Product Development, Verification and Validation (V&V), Laboratory Developed Tests (LDTs), Design Control, Risk Assessment, Quality, Regulatory, CAP/CLIA, CLSI, RUO, GXP.