Qi Li
Associate Director Project Team Leader • Portfolio & Project Mgmt (BRC) @ Novartis
About
Accomplished Director of Research and Analytical Development team in the biopharmaceutical industry, with over 14 years of experience and expertise in immunology and analytical assays. Proven track record in the development and optimization of analytical strategies to support pre-clinical, clinical and CMC teams. Motivational and engaged team leader with excellent communication and interpersonal skills.
United States
Greater Boston
Pharmaceuticals
Molecular Biology, Biochemistry, Cell Culture, Cell Biology, Genetics, Immunohistochemistry, Confocal Microscopy, Protein Purification, Molecular Cloning, Western Blotting, Real-Time Polymerase Chain Reaction (qPCR), Drug Discovery, Oncology, Protein Expression, ELISA, Fluorescence Microscopy, Immunofluorescence, Live imaging, Super-resolution imaging, in Situ Hybridization
Experience

Director, Research & Pre-clinical Development
HilleVax
Boston, Massachusetts, United States

Research Instructor
Worcester, Massachusetts, United States
1. Led the plate-based screening and identification of small molecule compounds (palmitoylation inhibitors of transcription factor) from library to inhibit the GI and Eye cancer (intestinal adenocarcinoma and uveal melanoma). 2. Developed and implemented the in vitro, in vivo, and ex vivo (3D culture organoid and solid tumor spheroids) models to evaluate the efficacy of leading candidate in inhibiting solid tumors initiation and progression in eye, liver, and gastrointestinal tract. 3. Generated Uveal Melanoma mouse disease model induced by AAV and lentivirus-based transgene delivery.

Postdoctoral Fellowship
Worcester, Massachusetts, United States
1. Discovered the function and regulation of oncogenic signaling pathways (Wnt, G-protein-coupled receptors and Hippo) in the process of tumor initiation and progression in uveal melanoma and intestinal adenocarcinoma. 2. Genetically and functionally explored the novel upstream kinases (MAP4Ks family members) of Hippo pathway in regulating cell proliferation and organ growth.
Qi Li's Contact Information
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