Priya Saikumar Lakshmi, PhD
Senior Scientist @ Hillstar Bio
About
My interest is in pioneering T cell therapies, a mission that aligns with my doctoral research in immunology. With over 9 years of experience in the field, I've honed my expertise in flow cytometry and T cell immunology, developing a deep understanding of immune responses in autoimmunity cancer. Our team's collaborative efforts contribute to groundbreaking developments in cell therapy. As a Scientist, I leverage these competencies to explore inflammation in tissues and responses to curb them. The transition from academic research to industry has amplified my impact, working towards delivering potential therapeutic solutions to those in need. My dedication to immunology is driven by a commitment to contribute to meaningful advancements in healthcare.
United States
Waltham
Biotechnology
Gene Editing, Crispr, Technical Writing, ELISA, Tissue Culture, Immunoprecipitation, Flow Cytometry, mammalian cell culture, Bacterial Culture, Bacterial Transformation, Transfection, DNA/RNA isolation, Western Blotting, Immunostaining, Affinity Chromatography, Gel Electrophoresis, Mammalian Cell Culture, Fluorescence Microscopy, SDS-PAGE, Cell
Experience
Senior Scientist
Hillstar Bio
Boston, Massachusetts, United States
Scientist II
GentiBio
In my role as a Scientist II at GentiBio, I contributed to the authoring of IND-enabling study reports and supported pre-IND regulatory briefing books for our lead asset, GNTI-122. Additionally, I designed and executed DC-enabling pharmacology and pharmacokinetics studies for our second preclinical asset, GNTI-823, focusing on inflammation research.
Scientist
GentiBio
Boston, Massachusetts, United States
In my role as a Scientist at GentiBio in Boston, MA, I supported the lab relocation and buildout, utilized CRISPR technology for T cell genome engineering, and developed expertise in off-target editing impacts. I also helped develop assays to measure Treg cell function using Flow cytometry.
Graduate Student Researcher
UMass Chan Medical School
worcester, united states
As a Graduate Student Researcher, I utilized cutting-edge technologies like sc-RNAseq and Flow cytometry to identify and characterize tumor-infiltrating lymphocytes in Burkitt Lymphoma. I optimized patient-derived tumor lines for drug sensitivity assays and conducted in vivo studies in humanized mouse models to evaluate targeted drug treatments.
Biological Scientist
Diabetes center
Gainesville, Florida, United States
In my role as a Biological Scientist, I designed and executed assays to culture regulatory T cells ex vivo, processed human tissues for immunophenotyping, and gained experience with mice injections and organ harvesting for laboratory analysis.
Research Assistant
University of Florida
United States
Studying the role of T- regulatory cells in Type 1 diabetes. Involves culturing T- regulatory cells and analyzing cytokine environment - ICCS (Intra cellular cytokine assays) using Flow cytometry. Processing human blood and animal tissue for immune cell populations for immunophenotyping. Lentiviral production.
Graduate Research Assistant
University of Central Florida
Plant transformation with chloroplast mediated gene transfer Testing protein expression and characterization of functional activity using different assays. Purification studies using antibody mediated affinity chromatography. Stabilization studies for storage to ensure the proteins were stable. Animal handling-mice
Graduate Teaching Assistant
Immunology, Immuno Diagnostics Laboratory
Held group discussions for students - involves identifying concepts that are difficult for the students and aiding them by illustration and simplification of concepts. Mentoring students in Laboratory activities and grading student exams.
Education
UMass Chan Medical School
Immunology
University of Central Florida
Biotechnology
Anna University Chennai
Biotechnology
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