po-hung hsieh

fellow, clinical pharmacology and pharmacogenomics

About

Research in Carbohydrate Chemistry, Genome Editing, Cancer and Cardiovascular Biomarkers, Drug Safety and Discovery

Country

united states

City

los angeles

Industry

pharmaceuticals

Skill

research, molecular biology, life sciences, biotechnology, western blotting, cell culture, protein purification, assay development, drug discovery, clinical research, drug design, drug safety, quality control, mass spectrometry, nmr spectroscopy, chromatography, organic synthesis, analytical chemistry, carbohydrate chemistry, physical chemistry, natural products, animal models, microarray, structural analysis, hplc, pharmaceutical research, pharmaceutical industry, heparin, heparan sulfate, biochemistry, nuclear magnetic resonance, purification, high performance liquid chromatography

Experience

fellow, clinical pharmacology and pharmacogenomics

university of chicago

2019-1 - Present · 7 yrs 9 mos

teaching assistant

university of north carolina at chapel hill

2011-1 - 2012-1 · 1 yr 1 mo

˙ TA for compounding laboratory experiments

scientific consultant

glycan therapeutics

2015-1 - 2017-1 · 2 yrs 1 mo

* Contact email: hsieh.pohung@gmail.com * ˙ Natural product and carbohydrate structural characterization * ˙ Reagent and drug quality control

postdoctoral research associate

university of north carolina at chapel hill

2016-1 - 2016-1 · 1 mo

* ˙ Synthesis of unnatural and functionally labeled heparan sulfate oligosaccharide probe * ˙ Structural and conformational analysis of carbohydrates using NMR and MD simulation * ˙ Develop carbohydrate microarray to probe interactions between carbohydrate and protein

research assistant

university of north carolina at chapel hill

2011-1 - 2015-1 · 4 yrs 1 mo

* ˙ Heparan sulfate biosynthetic enzyme expression and purification * ˙ Chemoenzymatic synthesis of oligosaccharide anticoagulant * ˙ Characterization of oligosaccharide using chromatography, spectrometry, and spectroscopy

postdoctoral scientist in chemistry

caltech

2017-1 - Present · 9 yrs 9 mos

Education

national taiwan university

2002-1 - 2006-1 · 4 yrs 1 mo

Thesis ˙ Title: Isolation and analysis the heat-induced genes from heat-tolerant tomato ˙ Genetic manipulation and protein purification

chemistry

2017-1 - 2018-1 · 1 yr 1 mo

university of north carolina at chapel hill

philosophy

2011-1 - 2016-1 · 5 yrs 1 mo

Ph.D. Dissertation ˙ Title: Chemoenzymatic synthesis, structural characterization of oligosaccharides, and understanding heparan sulfate-protein interactions ˙ Project 1: Safeguard heparin safety: develop reversible anticoagulant and synthesize a library of standards ˙ Project 2: Utilize heparan sulfate based probes to investigate the interaction with proteins ˙ Project 3: Investigate the effect of sulfation on heparan sulfate conformations

national taiwan university

chemistry

2006-1 - 2008-1 · 2 yrs 1 mo

Master Thesis ˙ Title: Preparation of acylated rhamnosyl flavonoid analogs as α-glucosidase inhibitors ˙ Organic synthesis of flavonoid glycoside analogs and optimization of α-glucosidase assay ˙ Exploration of hypoglycemic agents derived from Cinnamomum and Machilus plants