Pierre Colombe Dromel

Advisor: Michael Young Ph.D. thesis research co-advised between MIT and Harvard Medical School

Advisor: Myron Spector, Alfredo Alexander Katz Ph.D. thesis research co-advised between MIT and Harvard Medical School

Advisor: Myron Spector, Ioannis Yannas Biomaterials-Tissue Interactions; Tissue Engineering and Organ Regeneration; and Design of Medical Devices and Implants, taught by Dr. Spector and Dr. Yannas.

Advisor: Alfredo Alexander Katz. Biomechanics and biomaterials research including Python algorithm design and simulation on tribotaxis walkers on lipid substrate.

Assistant to implementation of Smartwatches project. Creation and design of a ”module” for the Richemont Academy.

Title – Novel biomaterial-based stem cell therapies and treatment for retinal regeneration. Supervised by Dr. Myron Spector (Tissue engineering), Prof. Alexander-Katz (Soft matter) and Dr. Michael Young (Ophthalmology and Stem cells). • Developed and isolated novel cone progenitor cells to treat retinal dystrophy. Learned and worked on pre-clinical requirement, studies and process. • Enhanced retinal ganglion cell engraftment in vivo by the design of an interpenetrating network made of biocompatible polymers (gelatin and HA) serving as a delivery vehicle. • Showed the mechanical protection (shear stress) of hydrogels on in vivo injected retinal cells. • Acquired proficient skills in biomaterials and cell biology work, assays, data acquisition, statistical analysis and project designing. • Reviewed multiple manuscript (4-5) in the field of retina, tissue engineering and neuroscience.

Title – Detection of seizure activity and novel signals in TBI patients using Depth electrodes, EEG and other novel methods. Supervised by Dr. Martin Boutelle (Neuroscience). • Grade: First class with Distinction. • Creation of a software able to automatically detect seizures in traumatic brain injury patients. • Visit of King’s College hospital and TBI patient’s family. Worked on tight deadlines to aid supervisor with data for grant applications.

Title – A Direct Method for Predicting the High-Cycle Fatigue Regime in SMAs: Application to Nitinol Stents. Supervised by Dr. Michael Peigney (Mechanics of materials). • Grade: First class with Distinction. • Creation of a 3D model of Nitinol stent. Acquired knowledge of 3D modeling, finite element simulation, mechanical testing of materials.