Opher Kornfeld, PhD
Managing Director, Translational Research and Development @ SPARK NS
About
The need for therapies that cure or prevent debilitating neurological diseases with no disease-modifying treatments is dire. The most promising discoveries are locked behind the walls of academia due to an academia-industry know-how gap. I’ve worked in research environments both in academia and industry. My focus now is on bridging the gap that exists between them to ensure effective therapies get to patients who need them.
United States
Stanford
Research
Molecular Biology, Biochemistry, Immunofluorescence, High Throughput Computing, Molecular Cloning, Mammalian Cell Culture Models, Coding (MATLAB, R, Python), Peptide Synthesis, Animal models, In Vitro Assays, Live-cell imaging, Cell Line Generation, Drug Discovery, Research, Molecular Genetics
Experience
Managing Director, Translational Research and Development
SPARK NS
Menlo Park, California, United States
Founded in 2023, SPARK NS is an independent non-profit translational research organization dedicated to efficiently advancing promising neuroscience discoveries from the lab to the clinic. Through disease-specific 2-year programs, SPARK NS provides academic researchers with funding, education, mentorship, and networking opportunities to close gaps in knowledge and know-how and eliminate barriers that slow or prevent promising discoveries from directly benefiting patients.
Director, Translational Research and Development
SPARK NS
Menlo Park, California, United States
Founded in 2023, SPARK NS is an independent non-profit translational research organization dedicated to efficiently advancing promising neuroscience discoveries from the lab to the clinic. Through disease-specific 2-year programs, SPARK NS provides academic researchers with funding, education, mentorship, and networking opportunities to close gaps in knowledge and know-how and eliminate barriers that slow or prevent promising discoveries from directly benefiting patients.
Scientist 4
Genentech
South San Francisco, California, United States
Senior Principal Scientific Researcher
Genentech
South San Francisco, California, United States
Principal Scientific Researcher
Genentech
South San Francisco, California, United States
Senior Scientific Researcher
Genentech
South San Francisco, California
PhD Candidate, Chemical and Systems Biology
Stanford University School of Medicine
San Francisco Bay Area
PhD Candidate in the Lab of Professor Daria Mochly-Rosen. Designs, characterizes, and uses small peptide inhibitors as pharmacological tools to study mitochondrial function and dynamics. Key Projects: - Lead investigator in the development of a novel peptide inhibitor to investigate mitochondrial dynamics imbalance in neurodegeneration. - Established a lead therapeutic for Charcot-Marie-Tooth disease by designing activators and inhibitors of mitochondrial fusion. Was the primary Stanford researcher in this multi-institutional project. - Co-led an international effort to describe a novel mechanism for cardiac Troponin I’s (cTnI) role in ischemia-reperfusion damage.
Residential Academic Assistant
University of Oregon
Eugene, Oregon Area
Co-taught two freshman seminars: Science in the News and Forensic Sciences. Worked alongside Chemistry faculty, led study sessions, and organized extracurricular academic activities. Played a lead role in building a residential academic community.
Undergraduate Researcher
University of Oregon
Eugene, Oregon Area
Worked in the Laboratory of Professor Diane Hawley. Elucidated the relationship between RNA Polymerase II mutations and alternative polyadenylation.
Teaching Assistant and Biology Peer Tutor
University of Oregon
Eugene, Oregon Area
Taught General Biology (Mechanisms), Advanced Genetics and Molecular Biology, and Advanced Molecular Genetics Research Lab. Assisted students in class, office hours, and lab section.
Education
Stanford University School of Medicine
Chemical and Systems Biology
PhD Candidate in Chemical and Systems Biology
University of Oregon
Biochemistry
Summa Cum Laude Departmental Honors Phi Beta Kappa
Opher Kornfeld, PhD's Contact Information
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