olivier bornert

Scientific program manager @ European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe

About

Team and project leader scientist with extensive experience in delivering high quality therapeutics antibodies and proteins. Proven ability to lead, manage and prioritize projects in biochemistry, molecular biology and biophysics. I believe in collaborative work and love scientific challenge.

Country

Switzerland

City

Basel

Industry

Biotechnology

Skill

Protein Engineering, project management, Biochemistry, Protein Purification, Protein Expression, Expression de protéines, Purification des protéines, Cell Culture, Biotechnology, protein expression, Membrane Proteins, SPR, Biacore, AKTA, Affinity Purification, protein engineering, Management, Leadership

Experience

Scientific program manager

European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe

2026-4 - Present · 6 mos

Strasburgo

Principal Scientist

Bright Peak Therapeutics

2024-7 - 2026-3 · 1 yr 9 mos

Bâle

Senior Scientist - antibody and immunocytokines generation, QC and formulation

Bright Peak Therapeutics

2022-7 - 2024-7 · 2 yrs 1 mo

Project Leader

Domain Therapeutics

2022-3 - 2022-6 · 4 mos

Project leader for the development of an anti-CCR8 antibody for immuno-oncology from discovery to pre-clinical and clinical studies.

Principal Scientist - Team leader

IGI

2021-6 - 2022-3 · 10 mos

Senior Scientist

IGI

2020-6 - 2022-3 · 1 yr 10 mos

Epalinges, Vaud, Suisse

- Led a team of 2 scientist in charge of large scale expression and purification of Bi- and tri-specific antibodies (up to 200mg). Management of execution and planing of the experiments as well as objectives and performance of the team. - Led the implemention of a new automated pipeline for purification of antibodies using AKTA-based and magnetic beads purification. - Led projects related to large scale production of target proteins for multi-specific antibodies design.

Project Leader

The University of Freiburg

2014-3 - 2020-6 · 6 yrs 4 mos

Universität Klinikum

Collaborations: o ProQR therapeutics (The Netherlands) : Pre-clinical study of a RNA-based drug - This project led to a Phase 1/2 clinical trial (WINGS therapeutics - USA) o EU funded project with partners from The Netherlands and Austria - Development of biochemical and cellular assays for functional characterization of collagens - Pre-clinical study: in vitro and in vivo evaluation of RNA-based drug candidates (ProQR therapeutics) - Research partnership and budget elaboration with industrial partners - Generation of specific CRISPR-Cas9 constructs for targeted deletion of specific domain in mouse and human collagen VII - Design and purification of antigens for production of domain specific antibodies - Identification (MS) and molecular characterization of new intracellular partners of collagen VII - Culture of primary and immortalized cells derived from patients

Research scientist, Ph.D. candidate

Bioxtal

2009-10 - 2013-9 · 4 yrs

Région de Strasbourg , France

Partnership-based research collaboration with academic partner: Simonin Lab - Research institute of the biotechnology school of Strasbourg - UMR7242 - university of strasbourg - Production and purification of soluble and membranes proteins (GPCRs) for biochemical, biophysical and crystallographic studies - Protein expression in yeast, bacteria and mammal cells - Development of Surface Plasmon Resonance and AlphaScreen based assays for GPCRs - Characterization of a novel protein-protein interaction motif implicated in the interaction of GPCRs with an intracellular partner (Bornert et al., 2013) - Molecular characterization of protein-membrane receptors (GPCRs) interactions with NMR - Collaborative project with academic partner in Danmark for the development of a SPR-based assay to study the interaction of membrane receptors (GPCR)s with intracellular partners