Nitin Bagra
Senior Scientist @ Exactmer
About
I am a peptide chemist currently working for greener and sustainable process development technologies to access complex anti-diabetic peptides (GLP analogues) and other peptides. I also worked for development for Polyethylene glycols (PEGs) based ADCs Linker development. Prior to this, I gained extensive experience in peptide synthesis (SPPS) and downstream processing (LC), scale-up/technology transfer of peptide API /investigational peptide for discovery chemistry in GMP organization. During my doctorate, I gained knowledge in amino acid chemistry, peptide & peptidomimetics synthesis for Medicinal Chemistry and others.
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India
Pharmaceuticals
Liquid Phase Polymer Synthesis, Peptide process development, Nanostar Sieving, Microwave Assisted Peptide Synthesis, Validation & Scale up synthesis, Reverse Phase HPLC, Mirowave Assisted Peptide Syntheis, Organic-Peptide Chemistry, Chemistry development for non natural amino acid, Cross Coupling Reactions, Process Optimization (Manufacturing), Technology Transfer, Pharmacology, Pharmaceutics, Pharmacy, Project Management, Team Building, Environment, Health, and Safety (EHS), Risk Management, Corrective and Preventive Action (CAPA)
Experience
Senior Scientist
Exactmer
London, England, United Kingdom
(A) Leading development of sustainable and greener technologies to afford GLP type peptide using the Nanostar sieving, Business development and project writing. (B) Chemistry development and scale up of novel sequence defined polyethylene glycols-peptide conjugates for numerous applications (C) Solid Phase Oligonucleotide Synthesis
KTP Associate/ Postdoctoral Research Chemist
Queen Mary University of London
London, England, United Kingdom
Process development for Peptide APIs (Complex antidiabetic GLPs and other peptide) using Nanostar Sieving (linear and hybrid approach) Design, chemical development of multifunctional sequence defined monodisperse homo and hetero polyethylene glycols (PEG)-peptide/amino acids as antibody-drug conjugate (ADC) linker. Bioconjugation of ADC linkers (PEG based) with drug (fluorescent dye) & maleimide for generation of model ADC equivalents.
Senior Research Associate III (Deputy Manager)
USV PRIVATE LIMITED
Mumbai, Maharashtra, India
Working as Technical Lead in Peptide Process Development of Complex Peptide Molecules and other Peptide Drugs for Synthesis (SPPS), Peptide Modification, RP-HPLC Purification, API manufacturing, Characterisation, Regulatory Submission
Senior Research Associate II (Assistant Manager)
USV PRIVATE LIMITED
Mumbai, Maharashtra, India
Worked as Senior Peptide Chemist for Synthesis (SPPS), Peptide Modification and RP-HPLC Purification for Process Development of Peptide Generics and other Peptide Drugs
University Lecturer
Apeejay Stya Education (Svran Foundation)
Sohna, Gurgaon, India
Tutoring Theory and Conducting Experimental Sessions of Organic Chemistry, Medicinal Chemistry and Pharmaceutical Analysis to graduate students.
Researcher PHD Student
National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
Mohali, Punjab
Synthesis of Non Natural Amino Acids and Modified Amino Acids for Medicinal Chemistry, Synthesis of Peptide and Peptidomimetics for Anti-microbial activities in Solution Phase Chemistry and Solid Phase
M.S. (Pharm.) Medicinal Chemistry
National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
Mohali
Synthesis of Non-natural Amino Acids
Education
National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
Organic Chemistry, Spectroscopy, Separation Sciences, Biomolecular Chemistry
Nitin Bagra's Contact Information
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