Nicolas H.
Senior Scientist @ Novo Nordisk
About
Scientist with a background in receptor biology and hormone regulation. As a former Postdoc at Charité University Berlin, I focused on G-protein coupled receptors, specifically the melanocortin 4 receptor, which regulates appetite. My significant achievement has been capturing the appetite-inducing receptor state using cryo-electron microscopy. I have leveraged this to design potentially more effective anti-obesity drugs. My research toolbox includes molecular biology, membrane-protein expression, cell-based assays, and biophysical methods like fluorescence spectroscopy, cryo-EM and X-ray crystallography. I'm passionate about translating science into real-world solutions and open to collaborations in receptor biology and drug development. Feel free to connect if you'd like to explore potential opportunities.
Germany
Berlin
Pharmaceuticals
Microsoft Office, Research, Microsoft Excel, Teamwork, Molekularbiologie, Biochemie, Design Thinking, Coaching von Führungskräften, Vorträge, Kristallographie, Cell Culture, Scientific Writing, Protein Purification, Pharmacology, Structural Biology, Molecular Biology, Cell Biology, Data Processing, Cryogenic Electron Microscopy
Experience

PHD - Structural Biology of GPCRs
Berlin, Deutschland
Institute of Medical Physics and Biophysics Protein X-ray Crystallography & Signal Transduction - AG Scheerer Project; Structural Characterization of GPCR's in Appetite Control Laboratory methods: Cryo-EM, cell culture techniques, multiprotein complex formation, fluorescent based ligand binding assays, cell-based signaling assays, mRNA display, fermentation Cryo-EM data processing image data processing, cryosparc, RELION, python
Nicolas H.'s Contact Information
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