Naomi Wieser, PhD

Preclinical Scientist @ OM Pharma

About

I'm a scientist who is interested in understanding how bacteria affect our health, women's health and translating these findings into innovation.Focusing on nutrition and development, my PhD was a deep dive into how the neonatal gut and microbiome develop together, using multiomics to track tryptophan metabolism from the earliest days of life. A lot of time was spent growing intestinal organoids, wrangling NGS data in R, combiner with nutritional inputs and trying to make sense of what the microbiome was contributing in the first years of life. It was messy, fascinating work and it gave me a real appreciation for how much we still don't understand about mucosal immunology. Throughout this PhD I published 4 peer-reviewed reasearch articles!Since then I've moved into industry as a Preclinical Scientist at OM Pharma in Geneva. I manage accademic and GLP studies in mucosal immunology, work on biomarker strategies for clinical trials (Phase I-III), and collaborate cross-functionnaly with clinical, medical affaire and regulatory teams on bacterial lysates. What I find most exciting is when preclinical data starts informing clinical decisions. Dual Swiss-American, based in Geneva. Volleyball player since before I could analyze a dataset! I believe collaboration is the key to good research.

Country

Switzerland

City

Geneva Metropolitan Area

Industry

Health, Wellness & Fitness

Skill

In vivo, R, Toxicologie In Vitro, BSL2, Analyses Big Data, In vitro, Immunological understanding of Asthma, Urinary tract infections, Product development, Medical writing , Clinical research, Développement de produits, Preclinical data analysis and interpretation, Bacterial lysates and immunological research, Cross-functional collaboration and project management, Scientific communication and technical writing, Strong understanding of regulatory requirements and industry standards, Visualisation créative, Organisation d’événements, Développement organisationnel

Experience

Preclinical Scientist

OM Pharma

2025-1 - Present · 1 yr 9 mos

Genève, Suisse

As a Preclinical Scientist at OM Pharma, I am involved in advancing the development of bacterial lysates for therapeutic applications. Study design with accademic partners and CROs, my responsibilities center around generating and interpreting preclinical data that supports the company's innovative pipeline. I collaborate cross-functionally with research teams, product development and regulatory experts to ensure that our findings are aligned with both scientific and strategic goals. Furthermore, I am involved with the selecrion and validation of targets in clinical trials (P1-P3) in accordance to the company's objectives. With a deep understanding of preclinical models and data analysis, I contribute to the translation of cutting-edge research into clinical potential.

Communications Manager

Women on Stage®

2025-1 - 2025-8 · 8 mos

Suisse

Volunteering work as a Communications Manager part time to support women in the Science industry in Switzerland

Marie Curie-Skłodowska PhD Candidate

University of Amsterdam

2019-9 - 2024-4 · 4 yrs 8 mos

La Randstad, Pays-Bas

PhD program at the University of Amsterdam and Imperial College of London. In collaborations with Gut Research. My project focused on the benefits of Human milk on the development of neonatal gut. Using both metabolomics and 16S data, I analysed the metabolism of Typtophan by both the host and the microbiome. Furthermore, I investigated the effects of such metabolites on epithelial cell immunological activity. Skills: mammalian cell culture, multiomics data anaysis, 2D and 3D organoid cultuiing, co-culturing, microbiology and metabolomics.

Visiting PhD Candidate

Imperial College London

2022-3 - 2022-10 · 8 mos

Londres et périphérie, Royaume-Uni

Part of the Marie Curie-Skłodowska PhD consortium. Spent 8 months at Imperial College London to work under Pr. James Kinross and Pr. Julian Marchesi, to learn more about metabolomics and microbiology. Focusing on bacterial culture and data analysis.

Master Internship

CHUV | Lausanne university hospital

2018-5 - 2019-9 · 1 yr 5 mos

Région de Lausanne, Suisse

Master thesis on Giant Viruses, focusing on the development of these viruses in amoebas, under the supervision of Prof. Gilbert Greub and Dr. Ardisonne.