Nancy Lan Guo, Ph.D.

Nancy Lan Guo, Ph.D.

Chief Executive Officer @ Sostos Inc

About

Over the course of my career, I have led the development of an innovative AI software platform for cancer treatment, secured numerous patents, and conducted extensive research that has significantly impacted the fields of cancer care and computational medicinal chemistry. With more than a decade of experience, I have consistently demonstrated a deep commitment to addressing unmet clinical needs in cancer treatment. I've harnessed my expertise in innovative technology development to create a unique AI software platform that has garnered recognition and success in the field. This software, which has resulted in 61 peer-reviewed journal publications with over 3,800 citations, showcases my ability to bridge the gap between cutting-edge technology and practical applications in healthcare. In addition to the software platform, I've also developed a 7-gene lung cancer assay that accurately predicts the risk of tumor recurrence and metastasis while assessing the clinical benefits of chemotherapy. This groundbreaking invention has been validated in more than 1,600 patients, including a randomized phase 3 clinical trial. The FDA has recognized its significance by classifying it as a "Novel Technology" in their review process. My journey has not only been about software and assay development but also about identifying new drugs and new indications for existing drugs for the treatment of lung cancer and breast cancer. Through my patented AI software pipeline, I've made significant contributions to advancing cancer diagnostics and therapeutics. Below listed are some of my skills that can prove beneficial for other companies: Bioinformatics Program Management | Clinical Trial Validation | Research & Data Analysis | FDA Regulatory Knowledge | Computational Biology | Project Execution Always looking for new opportunities to expand my horizons, I enjoy taking on new challenges to leverage my knowledge and skills. I believe my experience, along with my work ethic, make me stand out in this highly competitive industry. If there are any further concerns or queries, don’t hesitate to get in touch with me. Email: lguo2@yahoo.com

Country

United States

City

Morgantown

Industry

Biotechnology

Skill

Community Outreach & Engagement, Team Coordination, Time Management, Analytical Skills, Emotional Intelligence, Relationship Building, Problem Analysis, Cross-functional Collaboration, Problem Resolution, Communication Skills, Teaching Methods, Epidemiological Analysis, Student Advising and Mentorship, Process Optimization, Operational Excellence, Technology Development, Policy & Procedures Compliance, Data Security & Privacy, Optimal Treatment Selection, Project Execution

Experience

Sostos Inc

Chief Executive Officer

Sostos Inc

LinkedIn
2024-6 - Present · 2 yrs 4 mos

Lead the strategic vision, growth, and commercialization of our AI-powered software platform technology for personalized cancer diagnostics and drug discovery.

Sostos Inc

Founder

Sostos Inc

LinkedIn
2020-10 - Present · 6 yrs

Morgantown, West Virginia, United States

As the founder of Sostos Inc, I have the privilege of pioneering a groundbreaking AI software platform technology, where we harness the incredible potential of AI and big data to uncover innovative treatment solutions for cancer patients. Along this journey, we are developing novel molecular diagnostic assays and identifying potential new drugs and new applications for existing ones, with a specific focus on the battle against lung cancer and breast cancer, all achieved through our patented AI software pipeline. Key Accomplishments: ►Invented 7-gene lung cancer assay, predicting tumor recurrence and metastasis risk while gauging clinical benefits of chemotherapy and validating in 1.6K+ patients, including randomized phase 3 clinical trial. ►Attained title of 'Novel Technology' by FDA while inching closer to diagnostic approval. ►Established AI software platform efficacy through 61 peer-reviewed journal publications with over 3.8k citations to address unmet clinical needs in cancer treatment. ►Functioned software to secure patents for 8 diagnostic assays and 21 groundbreaking compounds, revolutionizing drug development and uncovering new applications for existing drugs.

Thomas J. Watson College of Engineering and Applied Science, Binghamton University

AI/ML SUNY Empire Innovation Professor

Thomas J. Watson College of Engineering and Applied Science, Binghamton University

LinkedIn
2024-7 - Present · 2 yrs 3 mos

United States

I will promote multi-institutional and multidisciplinary research focusing on advancing AI in precision medicine.

West Virginia University

Professor

West Virginia University

LinkedIn
2015-7 - 2024-6 · 9 yrs

Occupational and Environmental Health Sciences/WVU Cancer Institute

While providing great education and mentorship to students, I take great pride in mentoring students and trainees, providing them with valuable guidance and instruction in specialized fields. My commitment extends to collaborating with colleagues, both within and outside the university, to foster interdisciplinary research and design innovative solutions for the challenges presented by cancer-related issues. My passion for advancing knowledge in occupational and environmental health science, clinical and translational science, and related areas has led me to engage in advanced research actively. This research aims to contribute to our understanding and the development of effective solutions in these critical areas. Key Accomplishments: ►Presented research at national and international conferences to contribute to academic and scientific community's knowledge and published research findings in reputable scientific journals. ►Accomplished research funding through grant applications and actively participated in fundraising efforts to support institute's research initiatives.

West Virginia University

Adjunct Graduate Faculty of Computer Science

West Virginia University

LinkedIn
2006-7 - 2024-6 · 18 yrs

Morgantown, WV

I'm dedicated to formulating and delivering impactful courses in computer science, ensuring that the curriculum consistently aligns with the high standards set by both the department and the university. In addition to the classroom, I actively engage with students, providing them with valuable support, including office hours, mentorship, and academic advising. My goal is to empower students to excel academically and achieve their career aspirations, fostering a learning environment where they can thrive. Key Accomplishments: ►Applied and participated in the assessment and evaluation of courses, programs, and student learning outcomes to improve overall quality. ►Adhered to university policies and procedures as well as promoting a safe and inclusive learning environment.

West Virginia University

Associate Professor

West Virginia University

LinkedIn
2011-7 - 2015 · 3 yrs

Morgantown, West Virginia, United States

Devoting my continuous efforts as an Associate Professor, I've been deeply committed to educating the public about crucial cancer-related issues, and I've actively promoted health and safety through the dissemination of my research results. My aim is to raise awareness and inspire positive health practices in the community. Furthermore, I've been diligent in ensuring that the research projects I'm involved with adhere to the stringent healthcare and research regulations that govern ethics, patient consent, and data security. These crucial safeguards are essential to maintain the highest standards of research integrity and patient well-being. Key Accomplishments: ► Assisted in the completion of administrative and leadership functions of departments, university, and professional organizations by helping shape the strategic direction of departments. ►Supervised collection, analysis, and interpretation of research data and maintained data security and integrity.

West Virginia University

Assistant Professor

West Virginia University

LinkedIn
2008 - 2011 · 3 yrs

Morgantown, West Virginia, United States

I've been passionate about sharing research findings, which I've accomplished by publishing in peer-reviewed journals and presenting at conferences. Through these efforts, I've contributed to the ongoing advancement of knowledge in the fields of community medicine and cancer research. In addition, I've actively fostered collaboration and teamwork by working closely with colleagues not only within the department but also across the university and with external organizations. These partnerships have been instrumental in promoting interdisciplinary research and educational initiatives, ultimately leading to comprehensive and innovative solutions in healthcare. Key Accomplishments: ►Examined research data by utilizing epidemiological and statistical methods to draw meaningful conclusions and insights. ►Cultivated relationships with local communities, healthcare providers, and public health organizations to address cancer-related issues and community health needs

West Virginia Clinical and Translational Science Institute

Program Director of Biomedical Informatics

West Virginia Clinical and Translational Science Institute

2009-3 - 2017-6 · 8 yrs 4 mos

Morgantown, WV

Taking the lead in developing, executing, and continually improving our biomedical informatics program, I ensured it aligns seamlessly with the organization's strategic goals and objectives. In my role, I've also been responsible for crafting and consistently updating educational curricula tailored for students, researchers, and professionals. This is essential to ensure that our programs remain current and relevant in this ever-evolving field. I've played a crucial role in assessing the quality of our education and research efforts, regularly evaluating the effectiveness of our programs. These assessments have been instrumental in guiding our program enhancements and maintaining a high standard of excellence. Key Accomplishments: ►Hired, administered, and mentored faculty and staff members for positive and innovative work environment. ►Administered program resources, including budget allocation and facilities for resourceful program operations.

West Virignia University

Research Assistant Professor

West Virignia University

2005-7 - 2008-9 · 3 yrs 3 mos

in Community Medicine and Mary Babb Randolph Cancer Center

The University of Southern Mississippi

Assistant Professor

The University of Southern Mississippi

LinkedIn
2004-8 - 2005-6 · 11 mos

in Computer Science

Education

West Virginia University

West Virginia University

LinkedIn

Computer and Information Science

2000 - 2004 · 4 yrs
West Virginia University

West Virginia University

LinkedIn

Computer Science

1997 - 2000 · 3 yrs
Peking University

Peking University

LinkedIn

Biochemistry and Molecular Biology

1992 - 1997 · 5 yrs

Nancy Lan Guo, Ph.D.'s Contact Information

Email

******@***.com

Phone

(**) *** ****

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