Minghao X.
Scientist 4 (gRED) @ Genentech
About
Drug delivery scientist who initiated active targeting nanoplatform and delivered meaningful data for T cell targeting at legacy Posieda Therapeutics. Apart from the expertise of targeted LNP, he also has extensive exposures at protein bioconjugation and profound understanding of small molecule drug discovery
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United States
Biotechnology
Antibodies, Ionizable lipid, lipid nanoparticle, Lipid, Drug Design, Lipids, Formulation, Bioconjugation
Experience
Scientist 4 (gRED)
Genentech
United States
Function lead of in vivo T cell delivery program Ligand bioconjugation and targeted LNP engineering
Senior Scientist
Poseida Therapeutics, Inc.
United States
T cell targeting and in vivo PoC of mRNA tLNP Method development for targeted LNP: Bioconjugation, Formulation optimization, Purification and Analytical Methods
Scientist 2
Poseida Therapeutics, Inc.
Extra-hepatic formulation investigation Discovery and optimization of novel biodegradable ionizable lipids
Research Scientist II
Georgia Institute of Technology
Polymer library and formulation discovery for liver DNA delivery program (by Intergalactic Therapeutics) Virus-Like Particle Conjugates and hybridomas (Ab) discovery against Fentanyls Reversible protein lysine bioconjugation, chemo-selectivity investigation, stability optimization
Postdoctoral Research Fellow
University of Utah
Click-to-Release linker design and protein/prodrug conjugate synthesis Investigation of linker lability, kinetics, side products and controlled release mechanism
Scientist
WuXi AppTec
Small Molecule Drug Discovery (SMDD)
Education
East China University of Science and Technology
Medicinal Chemistry and Chemical Biology
East China University of Science and Technology
Pharmaceutical Sciences
Minghao X.'s Contact Information
Phone
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