Melanie Nyuydzefe, MBA
Senior Director, Translation Medicine Operation and Procurement @ Graviton Bioscience
About
Highly motivated biomedical research scientist seeking to use strong scientific education and background towards a career Biopharmaceutical industry.
United States
New York
Biotechnology
ELISA, Transfection, Flow Cytometry, FACS, BLAST, PCR, Western Blotting, Gel Electrophoresis, Assay Development, Molecular Biology, Cell Culture, Protein Purification, Molecular Cloning, Co-IP, Immunoprecipitation, Biochemistry, Cell, DNA extraction, Protein Expression, In Vitro
Experience
Senior Director, Translation Medicine Operation and Procurement
Graviton Bioscience
New York, United States
Director, Operations and procurement
Graviton Bioscience Corp.
Senior Scientist & Lab Manager
Équilibre BioPharmaceuticals Corp.
New York, United States
scientist II
Kadmon, a Sanofi Company
New York, New York, United States
Scientist
Kadmon, a Sanofi Company
Greater New York City Area
-Working on the drug KD025, an orally available ROCK2 selective inhibitor for the treatment of autoimmune disease indications. -Screening in house developed compound library for activity. -Phase II clinical trials support of KD025 in Psoriasis and cGVHD -Publications in science signaling, PNAS and Blood
Research Associate
Kadmon, a Sanofi Company
Greater New York City Area
I am currently working on the first orally available ROCK2 selective inhibitor (KD025) for the treatment of autoimmune disease indications. Exploring the molecular mechanism of ROCK2-mediated STAT3 Phosphorylation in Th17 cells, and the effects of ROCK2 inhibition in human immune cells.
Research Associate
Avatar Biotechnologies, LLC
NY, NY
Project to develop an HIV immunogen prioritization assay based on isolated and characterized broadly neutralizing antibodies
Research associate
QIAGEN
Developed and ran two projects on ELISA signals optimization with QuantaRed Enhancer chemifluorescent HRP substrate and with Wellchampion blocking buffer.
Internship
Mount St. Mary's University
Searched for primer needed for analyzing RELN as an Autistic Gene, Performed PCR on autism patient DNA sample from members of the same family, and Performed Gel electrophoresis on the PCR samples and analyzed the photographs for presence of product
Internship
The Institute for Genomic Research
Rockville, MD
• Prepared PCR of Geobacter sulfurreducens cell DNA grown in different medium • Performed Gel electrophoresis on the PCR samples • Assisted with DNA microarray representing the genome of Geobacter sulfurreducens constructed for use in global gene expression profiling of cells under steady-state conditions with acetate as the electron donor and Fe(III) or fumarate as the electron acceptor.
Education
Zicklin School of Business
New York University - Polytechnic School of Engineering
Biotechnology
Biotechnology
Mount St. Mary's University
Biochemistry
Biochemistry
Melanie Nyuydzefe, MBA's Contact Information
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