Mehmet T.

Director of Research- mRNA Cell Therapy and Bispesific Ab Development for Autoimmunity and Cancers

About

An accomplished result-driven professional physician scientist with over 15 years of experience in clinical and research projects. Proven ability to adapt to dynamic environments, rapidly acquire new knowledge, and effectively contribute to the success of clinical trial projects. Recognized for exceptional teaching, supervisory, and mentoring skills, with a keen focus on fostering excellence across diverse departments.

Country

United States

City

Washington DC-Baltimore Area

Industry

Biotechnology

Skill

Cancer Biology, Next-Generation Sequencing (NGS), Drug Development, Cross-functional Team Leadership, Molecular & Cellular Biology, Good Clinical Practice (GCP), ICH, Project Management, Pathology, Stem Cell Research, Cell Therapy, Autoimmune Diseases, Cancer Immunotherapy, Immunology, Medicine, Mentoring, Translational Medicine, Clinical Development, Manuscript, Laboratory Skills

Experience

Director of Research- mRNA Cell Therapy and Bispesific Ab Development for Autoimmunity and Cancers

Cartesian Therapeutics

2021-2 - Present · 5 yrs 8 mos

Autoimmune diseases and cancers cell therapy development. Autogenic CAR-T, allogeneic bispecific BiTE antibody clinical development. Translational medicine development for dose-response biomarker strategy. CRO/contractor oversight and management, mechanism of action, PD/PK. Supported IND, cGMP, mRNA optimization.

Project Scientist- Oncology Regenerative Medicine Preclinical Development

UC Irvine

2020-7 - 2021-2 · 8 mos

Epithelial regeneration in solid tumors in preclinical development. Supervising UCI master students in immunohistochemistry and immunofluorescence imaging.

Postdoctoral Fellow- Neurology Translational Medicine

Baylor College of Medicine

2017-10 - 2020-7 · 2 yrs 10 mos

Translational medicine hippocampal adult neurogenesis projects. Preclinical candidate drug screening. Metabolomics and lipidomic in vivo data analyzing the different brain areas for preclinical proof of concept. In vivo plasma membrane isolation in different brain regions and validated different lipid types for preclinical proof of concept. Led the lab safety protocols. Supervised the Rice University undergraduate students in designing laboratory experiments. Trained and supervised the Baylor College of Medicine SMART program students in stereotaxic mouse brain surgery and adult neurogenesis BrdU tissue imaging experiment design. Trained the Baylor College of Medicine graduate students in genotyping and lipid fractionating by high-speed ultracentrifugation.

Scientist- Rare Genetic Diseases Translational Medicine

Albert Einstein College of Medicine

2015-10 - 2017-8 · 1 yr 11 mos

Translational medicine approach to establish the Wnt, Fgf8, and Noggin genetic models for vertebrate somitogenesis projects. Stochastic models for genetic expressions.

Associate Professor of Clinical Pathology- Chronic Degenerative Diseases Clinical Projects

Abant İzzet Baysal University

2010-1 - 2015-10 · 5 yrs 10 mos

Led the clinical trial for chronic degenerative pseudoexfoliation eye disease. Therapeutic drug monitoring of the digoxin in coronary heart disease. Led immunology and hematology clinical laboratories. Led the accreditation of the clinical laboratory methods. Mentored and supervised the graduate students and resident physicians. Lectures for Clinical Pathology and Human Metabolism to graduate and School of Medicine students.