Meagan Vaughn, PhD

Performs and assists with clinical research and regulatory activities across the drug development pathway. • Authoring, reviewing and editing a variety of clinical research documents for regulatory submission, ensuring compliance with ICH guidelines. • Protocol design and authoring. • Data Safety Management Board coordination. • Clinical project management support. • Feasibility evaluation for clinical studies. • Regulatory review of site essential documentation. • Participation in cross-functional teams to identify and execute process improvement solutions and strategies.

• Preparation of R01 grant proposal and budgets • Analysis of serologic data on exposure to tick-borne pathogens from a 2 year longitudinal study of outdoor workers in North Carolina

-Designed and implemented double-blind RCT to evaluate the effectiveness of factory-based permethrin impregnated clothing for the prevention of tick bites and tick-borne disease among outdoor workers in North Carolina -Preparation of R01 proposal, awarded in August 2010 -Management of study activities, including regulatory responsibilities (IRB and DSMB), recruitment and enrollment, data collection, and data management -Design of data collection instruments -Conducted data analyses and composed manuscripts -Managed study activities, analysis, and publication of pilot study conducted in 2009

Developed curriculum materials and assisted with pilot testing of the Central America Field Epidemiology Training Program

Teaching assistant for the following web-based courses: -Fundamentals of Public Health Surveillance -Methods in Field Epidemiology -Principles and Methods of Applied Infectious Disease Epidemiology -Global Infectious Disease Epidemiology

Trained study personnel and managed patient recruitment/enrollment for a study to determine the etiology of Southern Tick-Associated Rash Illness (STARI)

• Assisted in the design, construction, and testing of HIV vaccine candidates using VEE replicon particle vectors (VRP) • Performed in vitro assays to examine protein expression, cell viability, interferon response and RNA expression in response to VRP infection • Designed and implemented a quantitative real-time PCR assay to detect viral replication intermediates in VRP infected cells and tissues