Melissa Christine Holt

Senior Scientist - Computational Chemistry @ Neomorph, Inc.

About

Drug discovery scientist with 11 years of industry experience. I am a Medicinal Chemist with additional expertise within the areas of computer-aided drug design, structural biology, and biochemistry. I am passionate about translating pre-clinical discoveries into INDs.

Country

United States

City

San Diego

Industry

Pharmaceuticals

Skill

Covalent Warhead Design, Molecular Dynamics, Free Energy Perturbation, Targeted Protein Degradation, Medicinal Chemistry, Organic Chemistry, Occupational Safety, Hazardous Materials, Industrial Hygiene, Environment, Health, and Safety (EHS), Disaster Response, Analytical Chemistry, Drug Discovery, Emergency Preparedness, Emergency Spill Response, Hazardous Materials Training, Sequencing, Enzymology, Activity-Based Proteomics Profiling, DNA Encoded Libraries (DEL)

Experience

Senior Scientist - Computational Chemistry

Neomorph, Inc.

2025-8 - Present · 1 yr 2 mos

San Diego, California

Senior Scientist - Medicinal Chemistry

Odyssey Therapeutics

2022-5 - 2025-5 · 3 yrs 1 mo

Boston, MA & Ann Arbor, MI

Scientist - Medicinal Chemistry

Pfizer

2020-1 - 2022-5 · 2 yrs 5 mos

Boulder, CO

Scientist I - Medicinal Chemistry

Cayman Chemical

2018-4 - 2020-1 · 1 yr 10 mos

Ann Arbor, Michigan

Scientist I - Structural Biology Services

Cayman Chemical

2018-3 - 2018-4 · 2 mos

Operations Coordinator

Cayman Chemical

2017-11 - 2018-4 · 6 mos

Senior Associate Scientist - Structural Biology Services

Cayman Chemical

2016-11 - 2018-3 · 1 yr 5 mos

Associate Scientist - Structural Biology Group

Cayman Chemical

2015-4 - 2016-11 · 1 yr 8 mos

Graduate Student Research Assistant

University of Michigan

2011-8 - 2014-9 · 3 yrs 2 mos

Woodard Lab, Department of Medicinal Chemistry, College of Pharmacy

Undergraduate Research Assistant

University of Michigan

2010-1 - 2011-7 · 1 yr 7 mos

Garcia Lab, Department of Medicinal Chemistry, College of Pharmacy

Instrumentation Teaching Assistant, Undergraduate Student Instructor

University of Michigan

2008-9 - 2011-5 · 2 yrs 9 mos

Department of Chemistry

Undergraduate Research Assistant

University of Michigan

2009-1 - 2009-9 · 9 mos

Barbehenn Lab, Department of Molecular, Cellular and Developmental Biology

Intern - Molecular Biology Group

Coriell Institute for Medical Research

2008-5 - 2008-8 · 4 mos

Camden, New Jersey

Education

University of Michigan

Medicinal Chemistry

2011 - 2013 · 2 yrs

University of Michigan

Biochemisty

2007 - 2011 · 4 yrs