Matt Edwards, MBA
Vice President Technical Operations @ Affinia Therapeutics
About
I am a strategic AAV process development leader and CMC project manager with deep expertise across drug discovery, from target identification to IND filing. I thrive at leading cross-functional teams, developing and executing strategies that accelerate development timelines, optimize processes, and deliver innovative therapies to patients. Passionate about translating complex science into actionable programs, I focus on creating measurable impact and advancing transformative treatments that address unmet medical needs. I am committed to driving programs that not only succeed scientifically but also make a real difference in patients’ lives.
United States
Littleton
Biotechnology
Epigenetics, ChIP, Chromatin Immunoprecipitation, Cell Culture, Molecular Biology, PCR, Biochemistry, Fluorescence Microscopy, Genetics, qPCR, Western Blotting, Immunohistochemistry, Microscopy, Cell Biology, Molecular Cloning, Flow Cytometry, Tissue Culture, Research, Cell, Gel Electrophoresis
Experience
Vice President Technical Operations
Affinia Therapeutics
• Lead a high-performing team driving AAV process development to support clinical programs, enabling timely delivery of preclinical and clinical-grade material. • Developed and implemented novel manufacturing methods, improving efficiency, scalability, and product consistency. • Act as primary CDMO relationship manager, successfully aligning external partners with program goals and ensuring smooth technology transfer. • Provide strategic guidance across programs, contributing to accelerated development timelines and advancing innovative therapies toward clinical milestones.
Senior Director, Head of Process Science
Affinia Therapeutics
Director of Process Science and Head of Vector Core
Affinia Therapeutics
Waltham MA
Associate Director, Technical Operations
Affinia Therapeutics
Waltham, Massachusetts, United States
Associate Director, Vector Development and Operations
LogicBio Therapeutics
Lexington, Massachusetts, United States
CMC project management. Manages team responsible for vector development and AAV production.
Manager, Vector Operations
LogicBio Therapeutics
Cambridge, Massachusetts, United States
CMC project management. AAV Vector Production.
Principal Research Associate
LogicBio Therapeutics
Cambridge, Massachusetts
R&D Vector Production. Process development.
Senior Research Associate
Translate Bio
Cambridge MA
Target identification and validation for rare diseases. Screening and platform development. Assay development. mRNA production.
Scientist
AstraZeneca
Walthan MA
Oncology Drug Discovery, Target Validation
Research Associate
Constellation Pharmaceuticals
Cambridge MA
Oncology Drug Discovery with an emphasis on epigenetic targets.
Research Assistant
Harvard University
Cambridge MA
Developmental biology using C. Elegans as model
Research Specialist, Lead
Emory University
Atlanta GA
Epigenetic regulation of development using C. elegans as a model.
Education
Isenberg School of Management, UMass Amherst
Entrepreneurship
The University of Georgia
Biology
Matt Edwards, MBA's Contact Information
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