marybeth pysz

marybeth pysz

senior principal research scientist, pharmacology

About

- PhD-level Research Scientist with 10+ years experience in cancer research - Variety of skills in vivo, in vitro, and ex vivo biology, including molecular imaging, molecular and cell biology, and microbiology - Interests: diagnosing and/or therapeutic treatment of cancer. - Specialties: In vivo molecular Imaging (US, PET/CT, BLI), small animal handling, mammalian cell culture & cell-based assays, protein & DNA/RNA expression analyses, microscopy, cloning & expression manipulations (virus or chemical transfection, overexpression/silencing), pharmacokinetics.

Country

united states

City

san bruno

Industry

pharmaceuticals

Skill

microscopy, molecular imaging, cell culture, in vivo, in vitro, western blotting, transfection, cancer, small animal imaging, facs, mouse surgery and injection, cell signaling, qpcr, immunostaining, cryosection, molecular cloning and expression, viral expression, northern blotting, sirna/shrna

Experience

west valley nuclear services

internship

west valley nuclear services

1995-6 - 1995-8 · 3 mos

Responsible for databasing radiation safety records (Paradox database system)

abbvie

senior principal research scientist, pharmacology

abbvie

2012-6 - Present · 14 yrs 4 mos

* Group Leader: Pharmacology and in vivo imaging for site * Manages Pharmacology group activities: team of 8 people * In vivo efficacy, PK, and tolerability study design, timeline management, and execution in mice * Led lab startup and biological application development for in vivo imaging * Supervises PK bioanalysis execution and data analysis for mouse PK studies * Pharmacology reports in support of IND applications * Orthotopic cancer xenograft mouse models * Project team support (e.g., data analyses; presentations) and strategy * Previous roles: * GLP/non-GLP PK/TK analysis and reporting for toxicology studies in mice, rats, and cynomolgus monkeys

praxair

internship

praxair

1996-6 - 1997-7 · 1 yr 2 mos

Converted plant monitoring data from MS-DOS to Windows based program. Designed Visual Basic program in Microsoft Excel to size and cost water chillers.

stanford university school of medicine

research scientist

stanford university school of medicine

2011-1 - 2012-5 · 1 yr 5 mos

* Lab management: responsible for ordering and supply management * Mentored and collaborated with coworkers on various lab projects * Managed projects involving several collaborations with other labs across Stanford University * Independent research focus studying molecular ultrasound imaging strategies for early detection/diagnosis of and therapeutic treatment monitoring of cancer * Subcutaneous and orthotopic xenograft, and transgenic mouse models of cancer * Working knowledge of bioluminescence, PET, and CT imaging.

stanford university school of medicine

postdoctoral research scientist

stanford university school of medicine

2008-11 - 2011-1 · 2 yrs 3 mos

* 2+ year fellowship in the Stanford Molecular Imaging Scholars Program * Worked with PI on grant applications * Authored/co-authored 14 publications & 1 book chapter in span of 3.5 years * Poster and oral presentations of work given at World Molecular Imaging Congress (WMIC) and AACR meetings

roswell park cancer institute

postdoctoral research scientist

roswell park cancer institute

2003-2 - 2008-10 · 5 yrs 9 mos

* 3 year Ruth L. Kirschstein postdoctoral fellowship awardee * Investigated the role of protein kinase C signaling in regulation of cyclin D1 expression in normal and neoplastic intestine. * Authored/co-authored 6 publications * Presented work in posters at AACR meetings and department seminars * in vitro skills including * overexpression & knockdown techniques using adenovirus & lentivirus expansion & transduction, * siRNA transient transfection of cultured cells, * cell line culture, * expression analyses: western & northern blot analysis, qPCR * longitudinal analysis of pharmacological treatments affecting cell signaling pathways * flow cytometry analysis of apoptosis and cell cycle

Education

university at buffalo

university at buffalo

chemical engineering

1993-1 - 1997-1 · 4 yrs 1 mo

Minors in Math, Computer Science"]

north carolina state university

north carolina state university

chemical engineering

1997-1 - 2003-1 · 6 yrs 1 mo

Minor in Biotechnology","- Growth of and characterization of differential gene expression of biofilm formation and heat shock response by hyperthermophilic archae and bacteria","- Authored/co-authored 6 publications and 1 book chapter"]

marybeth pysz's Contact Information

Email

******@***.com

Phone

(**) *** ****

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