Manu Chakravarthy MD, PhD

Manu Chakravarthy MD, PhD

SVP and Global Head of Cardiovascular, Renal and Metabolism Product Development, Roche-Genentech @ Roche

About

With over 20 years of experience as a physician-scientist, I am passionate about advancing the understanding and treatment of human diseases with unmet medical needs. I currently lead the research and development function at Carmot Therapeutics, Inc., a biotechnology company that leverages a novel drug discovery platform to create innovative therapies for metabolic conditions such as diabetes, obesity, and liver diseases. I have a proven track record of delivering results across the drug development continuum, from discovery to registration, with expertise in cellular signaling, translational medicine, clinical pharmacology, biomarker development, clinical development, and regulatory affairs. I have successfully managed multiple global clinical trials, led cross-functional teams, and established strategic partnerships with external stakeholders. I also have a strong academic background, with an MD and a PhD in cell biology and physiology, and a clinical assistant professorship at Rutgers New Jersey Medical School. I enjoy teaching and mentoring the next generation of scientists and clinicians, and I am always eager to learn from others and share my insights. My mission is to bring my creativity, vision, and collaboration skills to make a positive impact on patients' lives and health outcomes.

Country

United States

City

Greater Boston

Industry

Biotechnology

Skill

Leadership, Executive Management, Working with Investors, Drug Development, Diabetes, Biomarkers, Translational Medicine, Clinical Research, Clinical Development, Life Sciences, Clinical Trials, Metabolism, Pharmaceutical Industry, Endocrinology, Translational Research, Public-private Partnerships, Medicine, Drug Discovery, Biotechnology, Therapeutic Areas

Experience

Roche

SVP and Global Head of Cardiovascular, Renal and Metabolism Product Development, Roche-Genentech

Roche

LinkedIn
2024-5 - Present · 2 yrs 5 mos

Boston, Massachusetts, United States

Rutgers New Jersey Medical School

Clinical Asst. Professor of Medicine

Rutgers New Jersey Medical School

LinkedIn
2009-7 - Present · 17 yrs 3 mos

New Jersey, United States

Teaching Medical Students, Residents, and Endocrine Fellows; attend on the out-patient Lipid Clinic

Carmot Therapeutics, Inc.

Executive Vice President, Head of R&D and Chief Medical Officer

Carmot Therapeutics, Inc.

LinkedIn
2021-3 - 2024-5 · 3 yrs 3 mos

Boston, Massachusetts, United States

Axcella

Executive Vice President Clinical Development and Chief Medical Officer

Axcella

LinkedIn
2020-8 - 2021-3 · 8 mos

Cambridge, Massachusetts, United States

Direct oversight of all phases of clinical development across several indications, regulatory affairs, quality, and scientific communications, and responsible for the strategic direction and oversight for Axcella’s clinical research and development activities.

Axcella

Senior Vice President Clinical Development and Chief Medical Officer

Axcella

LinkedIn
2017-8 - 2020-8 · 3 yrs 1 mo

Cambridge, Massachusetts, United States

Direct oversight of all phases of clinical development across several indications, regulatory affairs, quality, and scientific communications, and responsible for the strategic direction and oversight for Axcella’s clinical research and development activities.

Eli Lilly and Company

VP, Global Head, Innovation Strategy and External R&D, Endocrine and Cardiovascular

Eli Lilly and Company

LinkedIn
2015-8 - 2017-6 · 1 yr 11 mos

Responsible for external search and evaluate activities and R&D strategy in support of diabetes (+ complications) and cardio-renal efforts to shape and implement external innovation for Lilly.

Merck

Executive Director

Merck

LinkedIn
2013-5 - 2015-8 · 2 yrs 4 mos

Drug Development

Merck

Senior Director

Merck

LinkedIn
2012-2 - 2013-4 · 1 yr 3 mos

Drug Development

Merck

Director

Merck

LinkedIn
2011-10 - 2012-1 · 4 mos

Drug Development

Merck

Associate Director

Merck

LinkedIn
2008-9 - 2011-9 · 3 yrs 1 mo

Drug Development

Washington University in St. Louis

Instructor of Medicine

Washington University in St. Louis

LinkedIn
2006-7 - 2008-9 · 2 yrs 3 mos

Research focus on fatty acid synthase and developmental origns of metabolic disease. Attend physician on the endocrine in-patient serviceand out-patient endocrine and lipid clinics

Washington University in St. Louis

Postdoctoral Research Fellowship in Lipid Metabolism

Washington University in St. Louis

LinkedIn
2003-6 - 2006-6 · 3 yrs 1 mo

St Louis, Missouri, United States

Barnes-Jewish Hospital

Clinical Fellowship in Endocrinology, Diabetes & Metabolism

Barnes-Jewish Hospital

LinkedIn
2003-6 - 2006-6 · 3 yrs 1 mo

St Louis, Missouri, United States

Penn Medicine, University of Pennsylvania Health System

Intern and Resident in Internal Medicine

Penn Medicine, University of Pennsylvania Health System

LinkedIn
2001-6 - 2003-6 · 2 yrs 1 mo

Philadelphia, Pennsylvania, United States

Training in Internal Medicine

Education

UTHealth Houston

UTHealth Houston

LinkedIn

Medicine

1995 - 2001 · 6 yrs

Medical School (MD)

Harvard Kennedy School

Harvard Kennedy School

LinkedIn

Organizational Leadership and Decision Making

2012 - 2012
UT MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

UT MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

LinkedIn

Cell Biology & Physiology

1995 - 2000 · 5 yrs

PhD in Cell Biology & Physiology

Saint John's University

Saint John's University

LinkedIn

Liberal Arts and Sciences, General Studies and Humanities

1991 - 1995 · 4 yrs

BA double major in Biology and Chemistry

Manu Chakravarthy MD, PhD's Contact Information

Email

******@***.com

Phone

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