Manish Butte

Founder and Director @ Rarefied Biosciences

About

My laboratory’s goal is to address fundamental and therapeutic questions in immunology by innovating approaches to visualize and manipulate T cells. The ultimate aim of our work is to manipulate T cells to control immunologically-mediated diseases, infection, cancer, and autoimmunity. As a pediatric immunologist, I care for children and adults with rare immune diseases, including primary immunodeficiencies, autoimmunity, or auto-inflammatory disorders. Specialties: Pediatric immunology, Primary immune deficiency, pediatric allergy, food allergy, asthma. T cell biology, mechanobiology, atomic force microscopy, costimulation

Country

United States

City

Los Angeles

Industry

Biotechnology

Skill

Cell, Immunology, Allergy, Pediatrics, Flow Cytometry, Food Allergies, Healthcare, Cell Signaling, Research, Biochemistry, Biotechnology, Antibodies, Drug Discovery, Asthma, Molecular Biology, Microscopy, Cancer, Translational Research, Cell Biology

Experience

Founder and Director

Rarefied Biosciences

2023-1 - Present · 3 yrs 9 mos

Los Angeles, California, United States

Offering hope and healing to children with rare immune diseases

Co-Founder and Advisor

Symphony Biosciences

2021-11 - Present · 4 yrs 11 mos

Professor and Division chief

UCLA

2020-7 - Present · 6 yrs 3 mos

The Division of Immunology, Allergy, and Rheumatology comprises clinical care, research, and education at UCLA in the Department of Pediatrics. Our clinical care encompasses the inborn errors of immunity (primary immune deficiencies and immune dysregulatory disorders), secondary immune deficiencies, pediatric rheumatological conditions including lupus and arthritis, autoinflammatory diseases, monogenic autoimmune disorders, food allergies, respiratory allergies, drug allergies, and other defects of tolerance. We conduct cutting-edge basic research in the areas of T cell biology and gene therapy. Our group performs translational and clinical research in gene therapies, immunomodulation to treat severe infections, food allergies, lupus, and other immune diseases. We run ACGME-certified programs in advanced fellowship training in Allergy and Immunology and Pediatric Rheumatology.

Associate Professor and Division Chief

UCLA

2016-10 - 2020-6 · 3 yrs 9 mos

Greater Los Angeles Area

Co-Founder and Advisor

Microvolution, LLC

2013-11 - Present · 12 yrs 11 mos

San Francisco Bay Area

Microvolution delivers software that deconvolves fluorescence microscopy images up to 200 times faster than other manufacturers by combining intelligent software programming with the power of a GPU (graphics processing unit).

Attending Physician

Stanford Medicine Children's Health

2009-12 - 2016-10 · 6 yrs 11 mos

Stanford, CA

I see pediatric and adult patients in the Center for Genetic Immune Diseases Clinic. The clinic provides comprehensive, multidisciplinary services for infants, children, adolescents, and adults with chronic or unusual infections or primary immune deficiencies.

Assistant Professor

Stanford University

2009-11 - 2016-10 · 7 yrs

Stanford, CA

My research and teaching focus on cellular biophysics and immunology. We study how cells of the immune system are influenced in health and disease. I also care for children and adults with disorders of the immune system: primary immunodeficiencies and defects in tolerance such as asthma, allergies, and autoimmunity.